Recruiting NCT07497880
Efficacy and Safety of Oral KAI-7535 in Adult Participants Living With Obesity or Overweight With at Least 1 Weight-Related Comorbidity
Obesity · Overweight
Endocrinology
4,154 trials in this section
Not yet recruiting NCT07731256
Semaglutide for Low Back Pain
Lower Back Pain · Obesity (BMI>30) · Chronic Lower Back Pain
Not yet recruiting NCT07653464
Interplay of Central and Peripheral Vascular Effects of Insulin in Obesity
Obesity (BMI>30) · Insulin Resistance
Recruiting NCT07728669
Digital Dietary Intervention for Patients Receiving GLP-1 Receptor Agonist Therapy
Type 2 Diabetes Mellitus (T2DM) · Obesity (Disorder) · Overweight
Recruiting NCT07457034
Digital Follow-Up and Nursing Education in Bariatric Surgery Patients
Obesity (BMI > 35) · Bariatric Surgery
Recruiting NCT07732426
Effects of Semaglutide on Brain Dopamine Responses to Food Cues in Adults With Obesity and Food Addiction Tendencies
Food Addiction Tendency · Obesity · Overweight
Not yet recruiting NCT06645769
Na-Phenylbutyrate VAscular Trial
Diabetes
Recruiting NCT07622628
AIM-MET: AI-Guided Microbiome-Targeted Nutrition for Glycemic Improvement in Type 2 Diabetes
Type 2 Diabetes · Diabetes Mellitus Type 2
Recruiting NCT02583646
Investigating the Impact of Obesity on Pubertal Development in Girls
Obesity · Puberty · Normal Physiology
Recruiting NCT07674628
SALUD-M: Acceptance Based Coping Skills for Hispanic/Latinx Military Patients With Type 2 Diabetes
Type 2 Diabetes
Recruiting NCT07722910
Observation of Iris Blood Flow Via OCTA in Diabetic Neovascular Glaucoma
Neovascular Glaucoma · Type 2 Diabetes
Recruiting NCT06524960
Denosumab for Type 1 Diabetes
Type 1 Diabetes
Recruiting NCT07553429
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated
Diabetic Macular Edema
Not yet recruiting NCT07729501
Multilingual Voice Calls to Adjust Long-Acting Insulin for Adults With Type 2 Diabetes and Low Health Literacy in Pakistan
Type 2 Diabetes Mellitus (T2DM) · Hyperglycemia Due to Type 2 Diabetes Mellitus
Not yet recruiting NCT07732400
A Study of VV-14303 for the Treatment of Metabolic Dysfunction-associated Steatohepatitis (MASH)
Metabolic Dysfunction-associated Steatohepatitis (MASH)
Not yet recruiting NCT07731308
Zirconia-Reinforced Glass Ionomer Versus Injectable Giomer in Class V Restorations
Class V Dental Caries, Type 2 Diabetes Mellitus · Giomer Technology; Injectable Resin Composite; Zirconia-Modified Glass Ionomer
Not yet recruiting NCT07731139
A Study to Learn How Different Amounts of the Study Medicine Called PF-08642534 Are Tolerated and Act in the Body of People Who Have Obesity
Obesity
Not yet recruiting NCT07732270
Evaluation of a Paraclinical Test for the Diagnosis of Arterial Insufficiency in Diabetic Patients With Foot Ulcers
Arterial Insufficiency
Not yet recruiting NCT07730567
A Study to Evaluate the Pharmacokinetic Interaction and the Safety of AD-236A and AD-236B
Hyperlipidemia · Diabete Type 2
Recruiting NCT07411222
Emotional Eating, Sleep Quality, Mental State and Metabolic Syndrome
Schizophrenia · Bipolar Disorder · Psychiatric Issue
Recruiting NCT06072963
COMMETS- Combination MCI Metabolic Syndrome
Alzheimer Disease · Mild Cognitive Impairment · Metabolic Syndrome
Not yet recruiting NCT07218653
Human Cerebrovascular Blood Flow and Sex Differences in Metabolic Syndrome
Metabolic Syndrome
Enrolling by invitation NCT06453187
A Modified Platform Trial of Multiple CAMPs for the Management of Diabetic Foot Ulcers and Venous Leg Ulcers
Diabetic Foot Ulcer · Venous Leg Ulcer
Not yet recruiting NCT07729332
Switching to Oral Weight Management Pharmacotherapy to Prevent Weight Regain After GLP-1 Therapy Discontinuation
Obesity
Not yet recruiting NCT07729553
Vitamin D Status and Lipid Profile in Obese Adults With Type 2 Diabetes
Type 2 Diabetes Mellitus · Obesity · Dyslipidemia
Recruiting NCT07728383
A Proof-of-Concept Study to Evaluate Topical-Lingual Semaglutide in Adults With Obesity
Obesity & Overweight
Recruiting NCT07156370
Salivary Cortisol and Hypercortisolism in Type 2 Diabetes
Hypercortisolism · Type 2 Diabetes (T2DM)
Recruiting NCT06654713
Commercial or Open Source Closed Loop Impact on Pregnancy Study
Type 1 Diabetes · Pregnancy, High Risk · Insulin Dependent Diabetes
Not yet recruiting NCT07728812
Pragmatic Trial to Study the Cost-Effectiveness of MyPhenome-RX Test to Guide Anti-Obesity Pharmacotherapy
Obesity & Overweight
Not yet recruiting NCT06627569
Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans
Overweight/Obesity · Stress
Not yet recruiting NCT07728318
Efficacy, Safety, and Treatment Satisfaction of Once-Weekly Tirzepatide in Obese Type 2 Diabetic Patients
Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight
Recruiting NCT05071898
Pharmacogenetics of Response to GLP1R Agonists
Obesity · Diabetes Type 2
Recruiting NCT05173714
Sit Less, Interact and Move More (SLIMM) 2 Study
Chronic Kidney Diseases · Obesity
Recruiting NCT07728240
Diet, Metabolic Health, and Exercise Responses
Diet Quality · Metabolic Health · Cognitive Function
Recruiting NCT06987903
Impact of a Perioperative Physical Exercise and Respiratory Physiotherapy Program on the Patient Undergoing Bariatric Surgery
Bariatric Surgery and Physical Activity · Obesity/Therapy · Bariatric Surgery Complications
Recruiting NCT06858787
Validating CGM for GDM
Gestational Diabetes Mellitus (GDM)
Not yet recruiting NCT07724431
A Phase 1, Double-blind, Randomized Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of Single Dose and Multiple Doses of CG-0416 in Healthy Participants.
Overweight and Obesity
Recruiting NCT07693231
A Study to Test How Well Different Doses of BI 3034701 Are Tolerated by Japanese Healthy People and Japanese People With Obesity or Overweight
Healthy · Obesity
Recruiting NCT06752369
Adapting Single Sessions Interventions for Type 1 Diabetes
Type 1 Diabetes (T1D)
Recruiting NCT06630182
Evaluation of the Impact of Psychological Profile on Diabetic Foot Wound Healing.
Type 2 Diabetes · Foot Wound
Not yet recruiting NCT07723820
Glycemic Velocity and Early Retinal Microvascular Change With GLP-1RA Versus SGLT2i Initiation in Type 2 Diabetes (GLIDE)
Type 2 Diabetes Mellitus · Diabetic Retinopathy (DR)
Not yet recruiting NCT07725809
A Study to Learn How the Study Medicine Called PF-08653945 is Taken up Into the Blood in Adults With Overweight or Obesity
Overweight · Obesity · Healthy
Recruiting NCT07702461
Determination of Resistance Training Status for Patients on Glucagon-Like Peptide-1 Receptor Agonists
Obesity & Overweight · Diabetes (DM)
Recruiting NCT07422220
Long-Term Effects of Walnut Consumption on Brain Function
Healthy · Brain Insulin Sensitivity · Cerebral Blood Flow
Not yet recruiting NCT07726381
Relation Between Glycemic Control and Retinal Microvascular Changes in Diabetic Patients Using OCTA
Diabetic Retinopathy (DR) · Retinal Microvascular Changes
Recruiting NCT05643144
Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes
Diabetes · Alzheimer's Disease (Incl Subtypes) · Dementia
Recruiting NCT07317310
The NTU JO-SMART Study
Knee Osteoarthristis · Diabetes (DM) · Obesity & Overweight
Not yet recruiting NCT07639684
Impact of Endoscopic Sleeve Gastroplasty (ESG) in Obese Adults With Type 2 Diabetes (T2D)
Type 2 Diabetes Mellitus (T2D) · Obesity (BMI>30)
Not yet recruiting NCT07726615
Time-Restricted Eating and Staple Food Reduction Combined With App-Supported Exercise for Weight and Glycemic Control
Obesity; Impaired Glucose Regulation; Prediabetes; Type 2 Diabetes Mellitus
Recruiting NCT07726680
GlycoQuest: An AI-Adaptive CGM-Integrated Serious Game for Pediatric Type 1 Diabetes
Type 1 Diabetes Mellitus (T1DM) · Diabetes Distress · Hypoglycemia (Diabetic)
Recruiting NCT07724340
A Study to Assess the Efficacy, Safety and Tolerability of AT673 Co-administered With Semaglutide in Adult Participants With Type 2 Diabetes (T2D) and Overweight or Obesity
Adults With Overweight/Obesity and Type 2 Diabetes
Recruiting NCT05912647
Enhancing Diabetes Management Approaches for Patients With Uncontrolled Diabetes
Diabetes · Diabetes Type 2
Recruiting NCT07463846
A Study to Evaluate ALN-2232 in Participants With Obesity
Obesity
Recruiting NCT07575399
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)
Obesity or Overweight
Not yet recruiting NCT07722546
A Study to Learn About The Effects of Felzartamab on Thyroid Function and Its Safety in Adults With Graves' Disease Ages 18 to 75 Years Old
Graves' Disease
Recruiting NCT07465224
A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus (T2DM)
Not yet recruiting NCT07720635
A Phase III Study of KHN939 in Chinese Patients With Moderate-to-Severe Active Thyroid Eye Disease
Thyroid Eye Disease
Recruiting NCT00428987
Physical and Behavioral Traits of Overweight and Obese Adults
Obesity · Healthy Volunteers
Recruiting NCT07399678
Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D
Overweight or Obese Adults · Overweight or Obese, Type 2 Diabetes
Recruiting NCT07721597
A Single and Multiple Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP6590 in Participants With Normal Weight, Overweight and Obesity
Healthy Participants Study · Overweight and Obese Adults · First in Man Study to Evaluate Initial Safety
Recruiting NCT07624071
A Study to Evaluate ALN-6222 in Participants With Obesity
Obesity
Recruiting NCT06287736
Spinal Cord Stimulation and Small Fiber Peripheral Neuropathy
Diabetic Peripheral Neuropathy
Recruiting NCT07599410
A Research Study to Investigate the Efficacy and Safety of HRS9531 Tablets in Participants With Type 2 Diabetes Mellitus
T2DM
Recruiting NCT06921720
Phosphorus-31 Spectroscopy in Phosphate Diabetes
Phosphate Diabetes · X-linked Hypophosphatemia
Enrolling by invitation NCT07496463
Setmelanotide to Treat Obesity in a Patient With Pseudohypoparathyroidism Type 1a (PHP1a)
Pseudohypoparathyroidism Type 1a · Obesity
Recruiting NCT07438405
An Open-label, Rollover Trial to Evaluate the Efficacy and Safety of AMG 732 in Participants With Thyroid Eye Disease
Thyroid Eye Disease
Not yet recruiting NCT07720648
A Phase III Study of KHN939 in Chinese Patients With Moderate-to-Severe Inactive Thyroid Eye Disease
Thyroid Eye Disease
Recruiting NCT05079399
Biomarker of Diabetic Retinopathy
Diabetic Retinopathy
Recruiting NCT07228195
SGLT2i Therapy in Islet Transplantation (SIT)
Partial Islet Function · TPIAT · Diabetes
Recruiting NCT07284979
Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes
Obesity
Recruiting NCT07599982
Safety Evaluation of MODI, an Insulin Titration Algorithm, in Adults With Diabetes
Type 1 Diabetes (T1D) · Type 2 Diabetes (T2D)
Enrolling by invitation NCT07712809
Intelligent Care Platform - Quasi-Experimental Trial
Diabetes in Children · Diabetes Type 1
Not yet recruiting NCT07720271
AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight
Overweight · Obesity
Recruiting NCT07675161
MiniMed Fit Payload Wear Pediatric Study
Diabetes (DM) · Diabetes (Insulin-requiring, Type 1 or Type 2) · Diabetes in Children
Recruiting NCT07595549
A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
Obesity · Overweight and/or Obesity · Overweight
Recruiting NCT07057817
The ACHILLS Trial; Application of Cerament in Heel Infection for Lower Limb Salvage
Osteomyelitis · Diabetes · Calcanectomy
Not yet recruiting NCT07621640
Brown Adipose Tissue as a Mechanistic Determinant of Semaglutide Treatment Response in Obesity (BAT-Sema Study)
Obesity · Metabolic Syndrome · Brown Adipose Tissue
Not yet recruiting NCT07519707
Video Intervention to Improve Understanding of Diabetic Retinopathy at Zuckerberg San Francisco General Hospital and Trauma Center
Diabetic Retinopathy (DR) · Macular Edema (ME)
Not yet recruiting NCT07718503
A Study on the Combination of Tongluo Huayu Formula in Treating RVO of Phlegm-Stasis Intertwinement Type: Based on the Mechanism of Systemic Metabolic Regulation Mediated by Gut Microbiota
Retinal Vein Occlusion
Not yet recruiting NCT07717515
Healthy Habits During and After Gestational Diabetes
GDM
Recruiting NCT07284875
Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes
Obesity · Overweight
Not yet recruiting NCT07652528
CGM-guided Patch Pump vs Basal-Bolus Injection for Steroid-Induced Hyperglycemia in Sudden Sensorineural Hearing Loss: SHIP Trial
Sudden Sensorineural Hearing Loss (SSNHL) · Prediabetes / Type 2 Diabetes
Recruiting NCT07069647
Artificial Intelligence-Aided Screening for Patients With Diabetic Retinopathy and Age-related Macular Degeneration in Family Medicine and Geriatric Medicine Outpatient Clinics
Age-Related Macular Degeneration (AMD) · Diabetic Retinopathy (DR)
Not yet recruiting NCT07720466
Salivary Function and Dental Changes During GLP-1 Therapy
Obesity · Dental Erosion · Saliva Collection
Recruiting NCT07457723
Gut Microbiome and Metabolic Health Study
Healthy Volunteers
Recruiting NCT07575932
A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)
Overweight · Obesity · Overweight and/or Obesity
Recruiting NCT06843499
Effectiveness and Cost-Effectiveness Evaluations of AI-Assisted Diagnostic Software (VeriSee) for Ophthalmic Disease Screening
Age-Related Macular Degeneration (AMD) · Diabetic Retinopathy (DR)
Recruiting NCT06390345
Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention
Chronic Obstructive Pulmonary Disease · Obstructive Sleep Apnea · Overweight and Obesity
Recruiting NCT04714892
Mechanisms Underlying Individual Variations of Taste and Smell in Obesity
Obesity
Recruiting NCT06672939
A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related Comorbidities
Obesity · Overweight
Not yet recruiting NCT07720388
Supporting Medtronic 780G Insulin Pump Adoption in Latino Patients: A Spanish - Language Training Initiative
Diabetes Mellitus, Type 1 Diabetes
Not yet recruiting NCT07645482
Frequency Rhythmic Electrical Modulated Stimulation Effect in Peripheral Neuropathy Patients Severity of Cases and Qol.
Peripheral Neuropathy With Type 2 Diabetes
Recruiting NCT07715955
Effect of Probiotics on Appetite Regulation in Adults With Overweight/Obesity
Healthy · Overweight (BMI > 25) · Overweight , Obesity
Recruiting NCT06497595
Lifestyle Intervention to Reduce the Risk of Sarcopenia in Adults With Diabetes & Obesity Treated With Semaglutide
Type 2 Diabetes Mellitus in Obese
Recruiting NCT06686537
Convergent Mechanisms Underlying Reprometabolic Syndrome in Women
Infertility, Female · Obesity
Not yet recruiting NCT07668401
AMAZE 13: A Research Study Investigating How Well the Medicine Zenagamtide Helps People in Asia With Excess Body Weight Lose Weight
Obesity · Overweight
Not yet recruiting NCT07717697
Finerenone for the Treatment of Type 2 Diabetes-Related Kidney Disease: Efficacy Observation and Related Factor Analysis
Type 2 Diabetes Mellitus · Diabetic Kidney Disease
Not yet recruiting NCT07716241
A Phase I Study of Single and Multiple Doses of HS-20136-2 Injection in Healthy or Obese Participants
Obesity
Recruiting NCT07036796
Effect of Melatonin in Patients With Diabetic Peripheral Neuropathy
Diabetic Peripheral Neuropathy · Diabetic Neuropathy · Diabetic Peripheral Neuropathy in Type 2 Diabetic Patients
Recruiting NCT07716059
Legume Flour Particle Size and Metabolic Responses to Bread
Type 2 Diabetes