Cardiology — clinical trials

Valvular Heart Disease Stenosis and Regurgitation (Diagnosis) · Pulmonary Hypertension (Diagnosis) · Heart Failure With Reduced Ejection Fraction (HFrEF; Diagnosis)

Not yet recruiting NCT07457879

Impact of the Reimbursement of Fibrinogen in Cardiac Surgery

— Observational Belgium

Cardiac Surgery

Recruiting NCT07325604

Effect of Neuromuscular Electrical Stimulation on Unilateral Central Facial Palsy

No phase Interventional Denmark

Facial Palsy · Stroke

Recruiting NCT07437222

Effect of Ginger Capsules on Inflammation, Oxidative Stress, and Endothelial Function

No phase Interventional Spain

Inflammation Biomarkers · Oxidative Stress · Cardiometabolic Risk Factors

Not yet recruiting NCT07250425

Development and Efficacy of a Novel, Cost-Effective Gait Training Device Utilized at Home for Stroke Survivors

No phase Interventional United States

Stroke · Neurological Diseases or Conditions · Hemiparesis;Poststroke/CVA

Recruiting NCT06394180

PeRforation EVents During ENdovascular Therapy for Acute Ischemic Stroke

— Observational Switzerland

Periprocedural Vessel Perforation · Acute Ischemic Stroke

Recruiting NCT07459387

REal-world Valued Outcomes of a noveL Balloon-in-basket pUlsed Field ablaTION Catheter for Atrial Fibrillation RegistrY

No phase Interventional Germany

Treatment of Atrial Fibrilation · Symptomatic Atrial Fibrillation

Recruiting NCT07457762

AIRDROP: Can we Improve Adherence to Inhaled Treatment for Pulmonary Arterial Hypertension?

No phase Interventional Brazil

Pulmonary Arterial Hypertension (PAH)

Recruiting NCT07223502

A Study Comparing the Clinical Benefit of Finerenone Versus a Fixed Dose Combination (FDC) of Extended-Release Torsemide and Spironolactone in Patients With Hypertension and Chronic Kidney Disease

Phase III Interventional United States

Hypertension (HTN)

Recruiting NCT06246396

Antihypertensive Mechanisms of Minocycline in Resistant Hypertension

Phase IV Interventional United States

Hypertension, Resistant to Conventional Therapy

Not yet recruiting NCT07456306

Artificial Intelligence-Driven Virtual Reality Rehabilitation for Upper Limb Recovery in Acute and Subacute Stroke Patients

No phase Interventional —

Stroke · Rehabilitation

Enrolling by invitation NCT07365501

Acute Effect of Nurse-assessed Remote Ischemic Preconditioning on Improving Vascular Parameters in Patients With Suspected Heart Failure With Preserved Ejection Fraction

No phase Interventional Spain

HF - Heart Failure

Not yet recruiting NCT07454707

Testing a New Treatment Strategy to Improve Secondary Stroke Prevention for Older Adults: The STROKE75+ Trial

Phase III Interventional —

Stroke, Ischemic

Recruiting NCT06054516

Hyperpolarized MRSI in Ischemic Heart Disease: A Metabolic Investigation of the Heart Muscle

— Observational Denmark

Ischemic Heart Disease

Enrolling by invitation NCT06828432

CTICU Device Study CRUISE

— Observational United States

Open Heart Surgery

Not yet recruiting NCT07456644

12-lead ECG Recording During Cardiac MRI

— Observational —

Magnetohydrodynamic Effect · Gradient-induced Voltages · ECG Signal Quality, Measured Inside the MRI Bore

Not yet recruiting NCT07456540

Comparison of Available Standard Pulse Field Ablation Methods for Pulmonary Vein Isolation for Treatment of Atrial Fibrillation

No phase Interventional Denmark

Atrial Fibrillation

Recruiting NCT07390331

A Patient Activation Approach to Implementing Depression Treatment in Cardiac Patients

No phase Interventional United States

Depression and CVD

Not yet recruiting NCT07456228

Emergency Stroke Unit With NeuAngio-CT (ESU-ACT)

— Observational China

Acute Ischemic Stroke

Not yet recruiting NCT07454954

The Effect of Blood Flow Restriction Training Combined With Transcranial Magnetic Stimulation on Limb Function in Hemiplegic Patients After Stroke

No phase Interventional —

Stroke · Hemiplegia

Recruiting NCT06945848

Venous Stenting Evaluation in Patients With Intracranial Hypertension Under Long-term Acetazolamide

No phase Interventional France

Idiopathic Intracranial Hypertension (IIH)

Enrolling by invitation NCT03083405

Selected Disorders and Sleep Bruxism

— Observational Poland

Sleep Bruxism · Hypertension · Thyroid Dysfunction

Not yet recruiting NCT07454096

Application of Radiomics for Diagnosis and Follow-up of Cardiovascular Device Infections: PREDICT Study

Phase IV Interventional Spain

Cardiac Disease · Device Related Infection

Recruiting NCT05328401

To Evaluate the Therapeutic Effect of Laser Acupuncture in Patients With Acute or Subacute Post Stroke Shoulder Pain

No phase Interventional Taiwan

Post Stroke Shoulder Pain

Recruiting NCT06566196

A Study of Hemodynamic Cardiopulmonary Exercise for CHD

No phase Interventional United States

Congenital Heart Disease

Recruiting NCT07453017

Electrical Impedance Tomography for Assessment of Pulmonary Hypertension

No phase Interventional Brazil

Pulmonary Hypertension · Pulmonary Thromboembolisms

Recruiting NCT04843683

StereoTactic Ablative RadioTherapy of Cardiac Arrhythmias

No phase Interventional Canada

Cardiac Arrhythmia

Not yet recruiting NCT07453030

Long-Term Outcomes of Selexipag in Schistosomiasis-Associated Pulmonary Arterial Hypertension

— Observational Brazil

Pulmonary Arterial Hypertension (PAH)

Recruiting NCT04237701

Real-Time Monitoring of Heart Failure Across the Yale New Haven Health System

— Observational United States

Heart Failure · Heart Failure With Reduced Ejection Fraction · Heart Failure With Preserved Ejection Fraction

Recruiting NCT06526117

Stroke Prevention in Nigeria 2 Trial

Phase IV Interventional Nigeria

Sickle Cell Disease · Stroke

Recruiting NCT06842745

Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia

Phase II Interventional United States

Aphasia · Stroke · Aphasia Following Cerebral Infarction

Recruiting NCT06514950

Yoga Breath Training to Improve Cardiorespiratory Synchrony in Spinal Cord Injury

No phase Interventional United States

Spinal Cord Injuries

Not yet recruiting NCT07452029

Construction of a Comprehensive Health Management Platform for Patients With Cardiovascular-Kidney-Metabolic Syndrome

No phase Interventional —

Cardiovascular-Kidney-Metabolic Syndrome

Recruiting NCT04701684

WE-TRUST (Workflow Optimization to Reduce Time to Endovascular Reperfusion for Ultra-fast Stroke Treatment)

No phase Interventional United States, Argentina +8

Stroke, Acute

Recruiting NCT07217678

Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use

Phase IV Interventional United States

Glaucoma · Open-Angle Glaucoma · Ocular Hypertension

Recruiting NCT07004673

18F FDG and 68Ga FAPI PET/MR Imaging of Carotid Artery Plaque Vulnerability: A Clinical Study in Carotid Artery Plaque Patients

— Observational China

Carotid Artery Plaque · Ischemic Stroke · PET / MR

Recruiting NCT04947657

The CoAGulation Biomarkers and Atrial Fibrillation (COAG-AF) Pilot Study

— Observational United States

Atrial Fibrillation

Recruiting NCT06055452

Effects of SGLT2 Inhibitors in Pre-heart Failure Populations With Hypertension

Phase IV Interventional China

Pre-Heart Failure · Hypertension

Recruiting NCT06400004

Lumason® Infusion vs. Bolus Administrations

Phase III Interventional United States

Heart Diseases

Recruiting NCT05081713

Locomotor Recovery and Compensation Post-stroke (LRC)

No phase Interventional United States

Stroke

Enrolling by invitation NCT05334784

Impella ECP Study (ECP Study) and Impella ECP Continued Access Protocol

No phase Interventional United States

High-Risk Percutaneous Coronary Intervention

Recruiting NCT07451522

Comparative Analysis of Analgesic Approaches in the Early Period After CABG

No phase Interventional Russia

CAD - Coronary Artery Disease · CABG · Analgesia Assessment

Not yet recruiting NCT07436299

Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation

— Observational United States, Belgium +8

Heart Failure (HF) · Atrial Fibrillation (AF)

Not yet recruiting NCT04657835

Multiparametric MRI Assessment of Atrial Heart Disease as a Predictor of Atrial Fibrillation After Myocardial Revascularization Surgery

No phase Interventional France

Postoperative Atrial Fibrillation

Recruiting NCT07451457

The Role of a Structured Patient Education Programme in the Complex Care of Patients With Heart Failure

— Observational Hungary

Heart Failure

Recruiting NCT07452276

Artificial Intelligence-Based Cognitive Training in Patients With Stroke

No phase Interventional Egypt

Post-Stroke Cognitive Impairment (PSCI) · Stroke · Artifical Intelligence

Recruiting NCT07254195

Assessment of an Intensive Motor Telerehabilitation Program for Stroke Patients

No phase Interventional France

Stroke

Recruiting NCT06220396

CArdioMEtabolic Function and Reserve Capacity in Healthy Adults: The CAMERA Study

No phase Interventional United States

Healthy

Enrolling by invitation NCT07354334

Effect of Listening to Surah Al-Inshirah (The Opening-Up of the Heart) After Cesarean Birth on Postpartum Outcomes

No phase Interventional Turkey (Türkiye)

Postpartum Depression · Maternal-Fetal Relations · Spirituality

Recruiting NCT04843371

PPG to Predict Ejection Fraction and Other Echographic Data in the General Population

— Observational United States

Valvular Heart Disease · Pericardial Disease · Cardiomyopathies

Recruiting NCT06753045

Health Electronic Assessment of Risks and Trends Using Biometric Equipment and Technology

— Observational United States

Heart Diseases

Recruiting NCT07447804

Diaphragm Morphology and Respiratory Muscle Strength in Subacute Hemiplegic Patients

— Observational Turkey (Türkiye)

Stroke · Hemiplegia Following Ischemic Stroke · Diaphragm Ultrasonography

Recruiting NCT06931470

A Pilot Feasibility and Acceptability Study of Remote ExerciSe Training mOdalities (PRESTO)

No phase Interventional United States

Cardiovascular Diseases

Not yet recruiting NCT07451860

Chronic Total Occlusion and Triglyceride-Glucose Index

— Observational Turkey (Türkiye)

CAD - Coronary Artery Disease · Chronic Total Occlusion (CTO) · Triglycerid Glucose Index

Recruiting NCT05935605

Pulmonary Hypertension in Left Heart Disease

— Observational United States

Pulmonary Hypertension · Pulmonary Vascular Disease · Left Heart Disease

Recruiting NCT05473871

Enhancing Capacity in Churches to Implement PA Programs

No phase Interventional United States

Cardiovascular Diseases

Recruiting NCT07315308

Preoperative Deep Parasternal Intercostal Plane Block and Intraoperative Opioid Use in Cardiac Surgery

No phase Interventional Turkey (Türkiye)

Postoperative Pain · Sternotomy · Opioid Consumption

Recruiting NCT07166731

High Coverage CARotid Stenting vs. Medical Management Alone to Prevent EmboliSm From symptomaTic Non-stenotic cARotid Disease (SyNC)

— Observational Germany

Carotid Artery Disease · Symptomatic Carotid Artery Stenosis · Carotid Artery Stenting

Recruiting NCT06916520

Prasugrel Monotherapy Reduced Dose in Acute and Chronic Coronary Syndrome Patients After Percutaneous Coronary Intervention (PROMOTE)

Phase IV Interventional Netherlands

Coronary Arterial Disease (CAD) · Percutaneous Coronary Intervention (PCI)

Not yet recruiting NCT07435870

Analgesia Nociception Index Monitoring in Trigeminal Cardiac Reflex During Nasal Septoplasty

— Observational Egypt

ENT Disease

Recruiting NCT05085210

Improving Visual Field Deficits With Noninvasive Brain Stimulation

No phase Interventional United States

Visual Field Defect, Peripheral · Stroke · Visual Impairment

Recruiting NCT07420153

Remote Ischemic Preconditioning and Postoperative Neuronal Injury

No phase Interventional Germany

Postoperative Neuronal Injury

Recruiting NCT07448532

Comparative Effects of Functional Electrical Stimulation and Mirror Therapy for Foot Clearance Among Patients With Sub-acute Stroke

No phase Interventional Pakistan

Stroke (Subacute)

Recruiting NCT06526650

'Ai Pono Cooking Demonstrations

No phase Interventional United States

Type 2 Diabetes · Hypertension · Dyslipidemias

Recruiting NCT04101188

Mechanisms Underlying the Protective Vascular Effects of Dietary Potassium in Humans

No phase Interventional United States

Cardiovascular Risk Factor

Recruiting NCT06526273

PILI 'Āina Household

No phase Interventional United States

Type 2 Diabetes · Hypertension · Dyslipidemias

Not yet recruiting NCT07449429

A Privacy-Preserving OCR-LLM System for Coronary Syndrome Subtyping From Admission HPI: Multicenter Validation in China and the US

— Observational —

Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)) · Acute Coronary Syndromes · ST-segment Elevation Myocardial Infarction (STEMI)

Enrolling by invitation NCT07222839