CAR-T & cell therapy

1,352 trials in this section

Recruiting NCT06486051

A Study of Atlacabtagene Autoleucel CAR T-cells for Adults With Relapsed Large B-cell Lymphoma

Phase II Interventional New Zealand

Large B-cell Lymphoma · Diffuse Large B-Cell Lymphoma, Not Otherwise Specified · Primary Mediastinal Large B-cell Lymphoma (PMBCL)

Recruiting NCT05237986

Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

— Observational United States

Lymphoma · Leukemia

Not yet recruiting NCT07509034

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

Phase I Interventional United States

Extensive-Stage Small Cell Lung Cancer · Extrapulmonary Neuroendocrine Carcinoma · Recurrent or Refractory

Recruiting NCT06514898

Adoptive T Cell Therapy, DC Vaccines, and Hematopoietic Stem Cells Combined With Immune checkPOINT Blockade in Patients With Medulloblastoma

Phase I Interventional United States

Recurrent Group 3 Medulloblastoma · Recurrent Group 4 (Non-SHH/Non-WNT) Medulloblastoma

Recruiting NCT06575374

Single Arm Pilot Trial of Letermovir for CMV Prophy in CAR T Cell

Phase II Interventional United States

Cell Therapy

Recruiting NCT05621291

A Multicenter Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-Cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymph...

No phase Interventional United States

B-All · Acute Lymphoblastic Leukemia

Recruiting NCT07751380

Multi-modular Chimeric Antigen Receptor T Cells tarGeting B7-H3 in Children, Teenage & Young Adult Sarcoma

Phase I Interventional United Kingdom

Sarcoma

Recruiting NCT06285825

A Pilot Study of Emapalumab for the Treatment of CAR T-Cell Therapy-Associated Prolonged Cytopenia

Phase II Interventional United States

Cytopenia

Not yet recruiting NCT07572136

Anti-CRLF2-R/TSLPR Chimeric Antigen Receptor T Cells (TSLPR-CART) in Participants With Recurrent or Refractory CRLF2-R/TSLPR-Overexpressing B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Phase I Interventional United States

B-All · Acute Lymphoblastic Leukemia

Recruiting NCT05809284

Determining the Mechanisms of Loss of CAR T Cell Persistence

— Observational United Kingdom

Acute Lymphoblastic Leukemia With Failed Remission · Acute Lymphoblastic Leukemia Not Having Achieved Remission · Acute Lymphoblastic Leukemia, Pediatric

Recruiting NCT07254806

A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease

Phase III Interventional United States

Degenerative Disc Disease

Recruiting NCT05990465

LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies

Phase I Interventional United States

Non Hodgkin Lymphoma · Diffuse Large B Cell Lymphoma · Follicular Lymphoma

Recruiting NCT04715191

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

Phase I Interventional United States

Liver Cancer · Rhabdomyosarcoma · Malignant Rhabdoid Tumor

Recruiting NCT07391657

A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

Phase III Interventional United States, Australia +13

Relapsed Refractory Multiple Myeloma

Recruiting NCT07249528

A Study of Voice as a Way to Monitor for Side Effects in People Receiving CAR T-Cell Therapy

— Observational United States

Non-hodgkin Lymphoma · Multiple Myeloma

Recruiting NCT07339111

Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis

Phase III Interventional United States

Knee Cartilage Defects

Recruiting NCT07451054

CD45BE-HSPC + CART-45 Cells

Phase I Interventional United States

B-Cell Non-Hodgkin Lymphoma (NHL) · Richter's Transformation · T-Cell Non-Hodgkin Lymphoma

Recruiting NCT06609928

FH-FOLR1 Chimeric Antigen Receptor T Cell Therapy for Treating Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia

Phase I Interventional United States

Recurrent Childhood Acute Myeloid Leukemia · Refractory Childhood Acute Myeloid Leukemia

Recruiting NCT07438067

EBV-AST Cell Therapy for EBV-Related Diseases After Stem Cell Transplantation

Phase I Interventional China

EBV-DNA Viremia

Not yet recruiting NCT07749976

GRACE: A Phase 1/2a Study of VTRU200 in Relapsed/Refractory AML, High-risk MDS, DLBCL Post CART Failure and Advanced Solid Tumors

Phase I / Phase II Interventional —

Acute Myeloid Leukemia · Diffuse Large B Cell Lymphoma (DLBCL) · High Risk Myelodysplastic Syndrome

Recruiting NCT06514794

A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)

Phase II Interventional United States, Australia

T-cell Acute Lymphoblastic Leukemia · Lymphoblastic Lymphoma

Recruiting NCT06828328

A Study of GC203 TIL in PDCA (RJ)

Early Phase I Interventional China

Pancreatic Cancer · Pancratic Ductal Adenocarcinoma · Treatment Side Effects

Recruiting NCT06703398

A Study of GC101 TIL in Advanced Melanoma

Phase II Interventional China

Melanoma

Recruiting NCT07371403

MB-CART19.1 in Relapsed/Refractory Acute Lymphoblastic Leukemia

No phase Interventional Jordan

Acute Lymphoblastic Leukemia · Acute Lymphoblastic Leukemia Recurrent · Acute Lymphoblastic Leukemia Refractory

Recruiting NCT04943913

Study of GC101 TIL in Brain Glioma (Soochow2)

Early Phase I Interventional China

Glioma

Recruiting NCT06116110

Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU

— Observational United States

Non Hodgkin Lymphoma · Refractory Diffuse Large B Cell Lymphoma (DLBCL) · Relapsed Diffuse Large B Cell Lymphoma

Recruiting NCT07673367

Nemtabrutinib With CAR T Therapy in Relapsed/Refractory Mantle Cell Lymphoma

Phase II Interventional United States

Recurrent Mantle Cell Lymphoma · Refractory Mantle Cell Lymphoma

Recruiting NCT07256756

A Study of GC203 TIL in Advanced Solid Tumors (NF)

Phase I Interventional China

Solid Tumors, Adult

Recruiting NCT04960072

A Study of GC101 TIL in r/r Gastrointestinal Tumors (10hospital)

Early Phase I Interventional China

Gastrointestinal Tumor

Recruiting NCT04967833

A Study of GC101 TIL in Advanced Solid Tumors (TR)

Early Phase I Interventional China

Advanced Solid Tumors

Recruiting NCT05087745

A Clinical Study on TIL for the Treatment of Advanced Solid Tumors

Early Phase I Interventional China

Advanced Solid Tumor · Tumor Infiltrating Lymphocytes · Treatment Side Effects

Not yet recruiting NCT07294872

A Study of TIL in Advanced Solid Tumors (CZ)

Phase I Interventional China

Solid Tumor, Adult

Recruiting NCT07744256

Adaptive Phase 1/2 Study of Dual-Target CAR-NK Cells in Relapsed/Refractory Small Cell Lung Cancer (SCLC)

Phase I / Phase II Interventional China

Small Cell Lung Cancer (SCLC) · Relapsed/Refractory SCLC · Extensive-stage SCLC

Enrolling by invitation NCT02473757

Gene Therapy Follow-up Protocol for People Previously Enrolled in CAR-T Cell Studies

— Observational United States

Lyphoma, B-Cell · Leukemia, B-cell · Multiple Myeloma

Recruiting NCT07680439

Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

Phase II Interventional United States

Diffuse Intrinsic Pontine Glioma · DIPG · Brain Tumor

Recruiting NCT07162038

Phase I Trial Integrating HLA-Haploidentical Anti-CD19 CAR-T Cells With Post-Transplantation Cyclophosphamide-Based HLA-Haploidentical Hematopoietic Cell Transplantation

Phase I Interventional United States

Hematologic Malignancies · Hematologic Neoplasms

Recruiting NCT07188558

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

Phase III Interventional United States

Large B-cell Lymphoma · Lymphoma, B-Cell · Relapsed Non-Hodgkin Lymphoma

Enrolling by invitation NCT06701201

A Long-Term Follow-Up Basket Study for Participants Treated With SynKIR Chimeric Antigen Receptor (CAR) T Cell Product

— Observational United States

Cancer

Recruiting NCT07297667

GCAR1, a Chimeric Antigen Receptor (CAR) T-CELL Therapy for Relapsed/Refractory GPNMB-Expressing Solid Tumours

Phase I Interventional Canada

Alveolar Soft Part Sarcoma · Renal Cell Carcinoma · Triple Negative Breast Cancer

Recruiting NCT04099797

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

Phase I Interventional United States

Diffuse Intrinsic Pontine Glioma · High Grade Glioma · Embryonal Tumor

Recruiting NCT06871410

Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Phase I Interventional United States

Recurrent Acute Myeloid Leukemia · Refractory Acute Myeloid Leukemia

Not yet recruiting NCT07335562

A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis

Phase III Interventional United States, Belgium +8

Systemic Sclerosis

Recruiting NCT07203404

A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With Autoimmune Diseases.

Early Phase I Interventional China

SLE · LN · ANCA Associated Vasculitis

Recruiting NCT06885697

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

Phase I Interventional United States

Mesothelioma · Neoplasms · Stomach Neoplasms

Not yet recruiting NCT07740317

Neurocognitive Trajectories After BCMA CAR-T

— Observational United States

Multiple Myeloma (MM) · CART Therapy · Refractory Multiple Myeloma (RRMM)

Recruiting NCT06991114

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

Phase II Interventional United States, Brazil +9

Refractory Rheumatoid Arthritis (RA) · Idiopathic Inflammatory Myopathies (IIMs) · Systemic Sclerosis (SSc)

Recruiting NCT07003295

Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy

Phase II Interventional United States

Recurrent Mantle Cell Lymphoma · Refractory Mantle Cell Lymphoma

Recruiting NCT07085104

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

Phase I Interventional United States, Canada

Systemic Lupus Erythematosus (With and Without Nephritis) · Idiopathic Inflammatory Myopathy · Systemic Sclerosis

Not yet recruiting NCT07683897

A Long-Term Follow-Up Trial for Participants Enrolled in CD5-deleted Chimeric Antigen Receptor Cells (Senza5 CART5) Trials

— Observational —

Participants Treated With Senza5

Recruiting NCT05442515

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies

Phase I / Phase II Interventional United States

B-NHL · B-Non Hodgkin Lymphoma · Acute Lymphocytic Leukemia

Enrolling by invitation NCT02503228

Clinical Registry Assessment of the Missouri Osteochondral Allograft Preservation System - MOPS

— Observational United States

Symptomatic Osteochondral Defect(s) · Cartilage, Meniscus, Ankle, Knee, Shoulder, Hip

Recruiting NCT06082531

Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis

No phase Interventional China

Platelets-rich Plasma · Osteoarthritis Knees Both · Meniscus Disorder

Recruiting NCT02727803

Personalized NK Cell Therapy in CBT

Phase II Interventional United States

Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive · Acute Biphenotypic Leukemia · Acute Lymphoblastic Leukemia

Recruiting NCT06947460

CD19-BCMA CART Cell Therapy for Refractory SLE-LN, SSc, and pSS-PAH

Phase I / Phase II Interventional China

Refractory Lupus Nephritis · Systemic Sclerosis · Primary Sjogren's Syndrome Combined With Pulmonary Hypertension

Recruiting NCT06218602

Pilot Trial of Fecal Microbiota Transplantation for Lymphoma Patients Receiving Axicabtagene Ciloleucel Therapy.

Phase II Interventional United States

Lymphoma

Recruiting NCT06193889

KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patients With Generalized Myasthenia Gravis

Phase II / Phase III Interventional United States, Australia +4

Myasthenia Gravis · Generalized Myasthenia Gravis

Recruiting NCT05773040

A Phase 1 Study of JV-213 Autologous CD79b-targeting Chimeric Antigen Receptor T-cell Therapy in Adults With Relapsed or Refractory B-cell Lymphomas

Phase I Interventional United States

Lymphomas · B-cell Lymphomas

Recruiting NCT06347068

Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells

Phase I Interventional United States

Breast Cancer · Relapse · Resistant Cancer

Recruiting NCT07639424

Study to Evaluate a New Cartilage Regeneration Platform for Knee Cartilage Repair

Phase IV Interventional South Korea

Cartilage Defects of the Knee

Not yet recruiting NCT07729826

C-CAR168 CAR T-Cell Therapy for the Treatment of Lupus Nephritis Refractory to Standard Therapy

Phase II Interventional —

Lupus Nephritis (LN) · Systemic Lupus Erythematosus (SLE)

Not yet recruiting NCT07729995

BAFF CAR-T Cells (LMY-922) for Treatment of Refractory Autoimmune Disease

Phase I Interventional United States

Rheumatoid Arthritis (RA) · Systemic Lupus Erthematosus (SLE) · Dermatomyositis (DM)

Recruiting NCT07173166

Non-Pharmacological Interventions for Neurotoxicity in Hematologic Patients Receiving CAR-T Therapy

No phase Interventional Spain

Hematologic Cancer

Recruiting NCT07411599

Dual Administration Of Intraperitoneal And Intravenous TROP2-Directed CAR-NK With TGF-Beta Receptor 2 (TGFBR2) Knock Out (KO) Therapy For Colorectal Cancer-Related Peritoneal Carcinomatosis: A Phase 1/2 Trial ("Chip-CRC Trial")

Phase I / Phase II Interventional United States

Colorectal Cancer · Peritoneal Metastases · Carcinomatosis

Recruiting NCT07397234

Thyroid Cartilage Plane VS Superior Laryngeal Nerve Space Block in Awake Tracheal Intubation

No phase Interventional China

Superior Laryngeal Nerve Block

Not yet recruiting NCT07727668

Iberdomide (CC-220) Priming to Improve T Cell Fitness Prior to Leukapheresis for Chimeric Antigen Receptor T Cell (CAR-T) Therapy for Relapsed/Refractory Multiple Myeloma (RRMM)

Early Phase I Interventional United States

Multiple Myeloma · Relapsed/Refractory Multiple Myeloma

Recruiting NCT07089121

Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune Disorders

Phase I / Phase II Interventional United States

Childhood-onset Systemic Lupus Erythematous · ANCA-Associated Vasculitis (AAV) · Juvenile Myasthenia Gravis

Recruiting NCT07490951

A Clinical Study of the Safety, Tolerability and Preliminary Efficacy of CD19/BCMA-targeted CAR-T Therapy in Refractory Autoimmune Diseases

No phase Interventional China

Autoimmune Diseases

Recruiting NCT07680803

Gene-Modified Stem Cell Therapy for Subjects With Transfusion-dependent Beta-thalassemia

Phase II Interventional Italy

Transfusion-dependent Beta-Thalassemia

Not yet recruiting NCT07725406

Low-Dose TBI Plus CAR T-Cell Therapy for Relapsed/Refractory DLBCL and Multiple Myeloma

Phase I Interventional United States

Relapsed or Refractory Diffuse Large B Cell Lymphoma (DLBCL) · Relapsed or Refractory Multiple Myeloma (MM)

Enrolling by invitation NCT03226704

Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing

— Observational United States

Leukemia · Lymphoma · Acute Lymphoblastic Leukemia

Recruiting NCT06915233

A Study of MACI in Patients Aged 17 to 65 Years With Symptomatic Chondral or Osteochondral Defects of the Ankle

Phase III Interventional United States

Chondral Defect · Articular Cartilage Defect

Recruiting NCT07250269

Study of GC012F, CAR-T Therapy Targeting CD19 and BCMA in Chinese Participants With Relapsed or Refractory AL Amyloidosis

Phase I Interventional China

Relapsed/Refractory AL Amyloidosis

Enrolling by invitation NCT07720310

Anti-CD19 CAR-T Cell Therapy for Patients With Refractory Systemic Lupus Erythematosus

— Observational Belarus

System Lupus Erythematosus(SLE)

Not yet recruiting NCT07551778

Allogeneic NK Cell Therapy Combined With Standard Maintenance Treatment in Advanced Solid Tumors

Phase I / Phase II Interventional —

NSCLC (Advanced Non-small Cell Lung Cancer) · Colorectal Cancer · Advanced Solid Tumors

Not yet recruiting NCT07648264

Single-arm Study of IgPro20 in Adults With Secondary Immune Deficiencies Due to Hematologic Malignancies Treated With B-cell Targeting Chimeric Antigen Receptor T-cell and T-cell Redirecting Therapies

Phase III Interventional United States, Belgium +9

Secondary Immune Deficiency

Recruiting NCT06328777

RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis

Phase I / Phase II Interventional United States

Systemic Sclerosis · Scleroderma

Recruiting NCT07211737

NKG2D.Zeta-NK Cell Conditioning With C7R.GD2.CAR-T Cells for Patients With Relapsed or Refractory Osteosarcoma or Neuroblastoma

Phase I Interventional United States

Relapsed Neuroblastoma · Refractory Neuroblastoma · Relapsed Osteosarcoma

Recruiting NCT06865664

FGFR4 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory Rhabdomyosarcoma

Phase I Interventional United States

Rhabdomyosarcoma

Recruiting NCT07200089

Recombinant Human IL-7 (NT-I7) in Relapsed/Refractory Multiple Myeloma Following BCMA CAR-T Therapy (Cilta-cel)

Phase I Interventional United States

Multiple Myeloma · Multiple Myeloma in Relapse · Multiple Myeloma, Refractory

Recruiting NCT06348797

Phase I Clinical Study of α-PD-L1/DLL3 CAR-T in Patients With R/R SCLC

Phase I Interventional China

Small Cell Lung Cancer Extensive Stage

Not yet recruiting NCT07717138

Study of the Biomechanical and Histological Properties of Septal, Auricular, and Costal Cartilage in the Context of Optimizing Total Nasal Reconstruction

— Observational France

Septoplasty · Rhinoseptoplasty · Rib Grafting

Recruiting NCT06771830

Evaluation of Pediatric eCART Implementation

No phase Interventional United States

Pediatric ALL · Sepsis

Recruiting NCT07715136

BCMA-CD19 cCAR-T for the Treatment of Refractory Inflammatory Myopathy

Phase I Interventional China

Inflammatory Myopathy

Recruiting NCT07715630

In Vivo PICX CAR-T Therapy for R/R Multiple Myeloma

Phase I Interventional China

Relapsed or Refractory Multiple Myeloma (RRMM)

Recruiting NCT07516249

Effects of Cartoons & Interactive Storytelling on Fear and Comfort in 6-9 Year Olds During Nebulizer Treatment

No phase Interventional Turkey (Türkiye)

Distraction Methods · Nursing Care

Recruiting NCT07098364

ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphoma

Phase I / Phase II Interventional United States

Recurrent Diffuse Large B-Cell Lymphoma · Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified · Recurrent Grade 3b Follicular Lymphoma

Not yet recruiting NCT07713511

INfections in Patients Treated With CAR-T

— Observational Italy

Relapsed Multiple Myeloma · Refractory Multiple Myeloma · B-Cell Non-Hodgkin Lymphoma

Not yet recruiting NCT07713459

A Phase II Study to Evaluate the Efficacy of UF-KURE19 Cells in Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphomas

Phase II Interventional —

Lymphoma Nonhodgkin · Marginal Zone B Cell Lymphoma · Diffuse Large B Cell Lymphoma (DLBCL)

Recruiting NCT07257419

CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma

Phase I Interventional United States

Relapsed Pediatric ALL · Hematopoietic Cell Transplantation · Hematologic Malignancy

Recruiting NCT07055477

A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL)

Phase I Interventional United States

Relapsed and/or Refractory Mature T Cell Malignancy · Peripheral T-Cell Lymphoma · Angioimmunoblastic T-cell Lymphoma

Recruiting NCT05052528

Fludarabine and Cyclophosphamide With or Without Rituximab Before CD19 Chimeric Antigen Receptor T Cells for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Phase I Interventional United States

Recurrent Diffuse Large B-Cell Lymphoma · Refractory Diffuse Large B-Cell Lymphoma

Recruiting NCT07645469

FH-WT1-E50 TCR T Cells With Azacitidine for the Treatment of Minimal Residual Disease Positive Acute Myeloid Leukemia

Phase I Interventional United States

Acute Myeloid Leukemia

Recruiting NCT07711561

Simple Non-cultured Endothelial Cell Therapy for Corneal Endothelial Dysfunction

Phase I Interventional India

Bullous Keratopathy · Corneal Endothelial Dystrophy

Recruiting NCT06364423

Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Leukemias

Phase I / Phase II Interventional United States

Leukemia, Lymphocytic, Chronic, B-Cell · B-Lymphocytic Leukemia, Chronic · B-Cell Chronic Lymphocytic Leukemia

Recruiting NCT07532525

Pomalidomide After CAR T-cell Therapy for the Treatment of Relapsed or Refractory CD19+ B-cell Leukemia or Lymphoma

Phase I Interventional United States

Recurrent B Acute Lymphoblastic Leukemia · Recurrent B-Cell Non-Hodgkin Lymphoma · Refractory B Acute Lymphoblastic Leukemia

Not yet recruiting NCT06703216

Pre-emptive Anakinra for Cytokine Event Reduction

Phase I / Phase II Interventional United States

B-Acute Lymphoblastic Leukemia · CAR-T Cell Therapy · Cytokine Release Syndrome

Recruiting NCT06247150

Tissue Immune Landscape of Graft Versus Host Disease After Allogeneic Stem Cell Transplantation (TIL-GVHD)

No phase Interventional France

Chronic Graft Versus Host Disease

Not yet recruiting NCT07709299

Safety and Feasibility of CIK Cell Therapy in HCC After Tumor Resection

Early Phase I Interventional Iran

Hepatocellular Carcinoma (HCC)

Not yet recruiting NCT07455747

Real-World Treatment of Extracranial Carotid Artery Disease With the ENROUTE™ Transcarotid Neuroprotection System

— Observational —

Extracranial Carotid Artery Disease · TCAR · Transcarotid Artery Revascularization

Recruiting NCT02830724

Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

Phase I / Phase II Interventional United States

Pancreatic Cancer · Renal Cell Cancer · Breast Cancer