Recruiting NCT06393374
Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
Triple-Negative Breast Cancer
Breast cancer
3,150 trials in this section
Not yet recruiting NCT06983691
Patient Navigation for HER2+ Metastatic Breast Cancer Patients Treated With Tucatinib
HER2+ Metastatic Breast Cancer (MBC)
Recruiting NCT06831955
LifEStyle Intervention to Enhance Efficacy of Neoadjuvant Therapy in Patients With Triple Negative Breast Cancer
Triple Negative Breast Cancer (TNBC), Early Setting
Not yet recruiting NCT07752550
Retlirafusp Alfa Combined With Chemotherapy or Fuzuloparib for Triple-Negative Breast Cancer
Triple-Negative Breast Cancer (TNBC)
Recruiting NCT05564377
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
Advanced Malignant Solid Neoplasm · Anatomic Stage III Breast Cancer AJCC v8 · Anatomic Stage IV Breast Cancer AJCC v8
Recruiting NCT07427394
Study to Evaluate the Safety and Tolerability of Camizestrant in Combination With Atirmociclib in Women With Advanced Breast Cancer
Advanced Breast Cancer
Recruiting NCT07060807
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
Breast Neoplasms
Not yet recruiting NCT07753226
A Study of SI-B036 in Patients With Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors
Breast Cancer · Solid Tumor
Recruiting NCT06966700
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
Breast Neoplasms · Triple Negative Breast Neoplasms · HR Low-Positive/HER2-Negative Breast Neoplasms
Recruiting NCT07242352
Marker - Adjusted Therapy Comparing Adjuvant Elacestrant With Standard Endocrine Treatment in Genomically and/or Clinically High-risk ER+/HER2- eBC
Breast Cancer · HR+/HER2- Breast Cancer
Recruiting NCT06841354
A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)
Triple Negative Breast Neoplasms
Recruiting NCT07264634
A Study to Assess the Amount of Palopegteriparatide in Breast Milk of Lactating Females Requiring YORVIPATH® (Palopegteriparatide)
Hypoparathyroidism
Not yet recruiting NCT07730125
Gene-edited T Regulatory Cells (CRG-150) for the Treatment of Relapsed/Refractory Malignancies
HR-positive, HER2-negative Breast Cancer · TNBC - Triple-Negative Breast Cancer · Prostate Cancer
Recruiting NCT04573231
Evaluation of PSMA in HER2- AR+ Metastatic Breast Cancer
Breast Cancer · HER2-negative Breast Cancer · Metastatic Breast Cancer
Enrolling by invitation NCT03762733
Tissue Acquisition and Genomics Analysis of Breast Cancer and Other Gynecologic Malignancies
Breast Cancer · Ovarian Cancer · Uterine Cancer
Recruiting NCT07739277
Transverse vs. Longitudinal Serratus Anterior Plane Block in Breast Surgery
Fascial Plane Block · Pain, Postoperative · Breast Surgery
Not yet recruiting NCT07752238
Diagnostic Prediction Model for De Novo Metastatic Breast Cancer
Breast Cancer · Metastatic Invasive Breast Cancer
Not yet recruiting NCT07619534
Collection of CSF Samples From Participants With Metastatic Triple Negative Breast Cancer (TNBC) and HER2+ Breast Cancer With no Prior History Nor Active Radiographically Detectable Brain Metastases
Breast Cancer · Breast Carcinoma · Cancer of the Breast
Recruiting NCT07391774
Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial
Anatomic Stage II Breast Cancer AJCC v8 · Anatomic Stage IIIA Breast Cancer AJCC v8 · Anatomic Stage IIIC Breast Cancer AJCC v8
Recruiting NCT05307705
A Study of LOXO-783 in Patients With Breast Cancer/Other Solid Tumors
Breast Cancer
Recruiting NCT07140172
Axillary Radiotherapy or Axillary Lymph Node Dissection in Patients With Clinically Node- Positive Breast Cancer Undergoing Upfront Tailored Axillary Surgery
Breast Cancer
Recruiting NCT06638307
A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer
Advanced Breast Cancer
Recruiting NCT06188520
A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors
ER+ HER2- Advanced Breast Cancer · High-grade Serous Ovarian Cancer (HGSOC)
Recruiting NCT07541040
Serratus vs ESP Block for Postoperative Pain in Unilateral Breast Surgery
Post Operative Pain · Opioid Use
Recruiting NCT06575192
Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants
Breast Reconstruction
Recruiting NCT07492641
BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease
HR+/HER2- Breast Cancer
Recruiting NCT06176261
DATO-BASE: DATOpotamab-deruxtecan for Breast Cancer Brain metAstaSEs
Breast Cancer · Breast Cancer Female · Metastatic Triple-Negative Breast Carcinoma
Recruiting NCT07222267
An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors
Breast Cancer · Advanced Solid Tumor
Recruiting NCT05386108
Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
Breast Neoplasms · Brain Neoplasms · Neoplasms by Site
Recruiting NCT06058377
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
Anatomic Stage II Breast Cancer AJCC v8 · Anatomic Stage III Breast Cancer AJCC v8 · HER2-Negative Breast Carcinoma
Recruiting NCT02102165
AURORA: Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer.
Metastatic Breast Cancer
Recruiting NCT05874297
Online Nutrition Education to Decrease the Side Effects of Chemotherapy in Patients With Breast Cancer
Anatomic Stage I Breast Cancer AJCC v8 · Anatomic Stage II Breast Cancer AJCC v8 · Anatomic Stage III Breast Cancer AJCC v8
Recruiting NCT06586047
Breast Cancer PSMA PET
Triple Negative Breast Cancer
Recruiting NCT07613151
Negative/Low Hormone Receptor and APOcrine Lobular Invasive Breast Carcinoma - A Real-World International Cohort Study
Lobular Breast Carcinoma
Recruiting NCT06999798
An Optimized Ultrasound Twinkling Marker for the Imaging of Lymph Nodes in Patients With Clinically Node-Positive Breast Cancer, The UTMOST2 Trial
Anatomic Stage II Breast Cancer AJCC v8 · Anatomic Stage III Breast Cancer AJCC v8 · Anatomic Stage IV Breast Cancer AJCC v8
Recruiting NCT06129747
Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast
Breast Cancer · Tumor, Breast
Recruiting NCT07287098
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
Breast Neoplasms
Recruiting NCT07368998
To Study the Effect of Inavolisib in Combination With Fulvestrant in Participants With Breast Cancer
Breast Cancer
Recruiting NCT07512271
Generative AI Patient Education Module for Breast Oncology
Breast Cancer · Metastatic Breast Cancer · Carcinoma of the Breast
Recruiting NCT07174336
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
Breast Neoplasms · Neoplasm Metastasis
Recruiting NCT05232916
Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
Breast Cancer
Recruiting NCT06274515
A Study to Investigate Mechanisms of Resistance to Breast Cancer Therapies
Breast Cancer
Not yet recruiting NCT07750340
Breast Cancer Molecular Subtypes and Skeletal Metastases Patterns on Bone Scintigraphy
Breast Cancer
Recruiting NCT06885203
Social and Environmental Determinants of Breast Cancer Survivorship: the Black Breast Cancer Survivor's Intervention (BBCSI)
Breast Cancer
Recruiting NCT06439693
The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer
Breast Cancer Female · Breast Cancer · Breast Cancer Metastatic
Recruiting NCT07674836
SPSIP Block Versus ESP Block for Chronic Pain After Unilateral Breast Surgery
Postoperative Pain · Opioid Use
Recruiting NCT05792150
PROOFS-Registry - Premenopausal Women With Breast Cancer Optimally Treated With OFS
Female Breast Cancer
Recruiting NCT06876714
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
Anatomic Stage I Breast Cancer AJCC v8 · Anatomic Stage II Breast Cancer AJCC v8 · Early Stage HER2+ Breast Cancer
Not yet recruiting NCT07178730
NeoAdjuvant Therapy Comparing Sacituzumab Govitecan+Pembrolizumab vs. SoC Chemotherapy in Clinical Stage II-III, Triple-negative Early Breast Cancer
Breast Cancer · Triple-negative Breast Cancer
Recruiting NCT07580105
Clinical Study to Assess the Safety and Performance of Kenko Breast AI+ Medical Device as an Aid to Breast Cancer Diagnosis in Adult Women
Breast Cancer
Recruiting NCT04794075
Therapeutic Education and Nursing Support Program for Supportive Care, in Patients Treated With Hormone Therapy for Non-metastatic Breast Cancer
Neoplasm of Breast
Not yet recruiting NCT07748208
A Study Evaluating the Safety of Inavolisib and Fulvestrant With or Without Palbociclib in Participants With Advanced Breast Cancer (ABC) and Type 2 Diabetes
Breast Cancer · Diabetes Type II
Recruiting NCT05422794
Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer
Anatomic Stage III Breast Cancer AJCC v8 · Anatomic Stage IV Breast Cancer AJCC v8 · Locally Advanced Triple-Negative Breast Carcinoma
Recruiting NCT06790693
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
Breast Cancer
Recruiting NCT07281833
Phase III Study to Evaluate the Safety, Efficacy, and Impact on Quality of Life of Capivasertib Alongside Standard-of-care Endocrine Treatment in Patients With HR+/HER2- Advanced Breast Cancer and Progression on Prior Endocrine-based Treatment
Breast Cancer · HR-positive Breast Cancer · Advanced Breast Cancer
Recruiting NCT05570253
A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer
Breast Cancer · Metastatic Triple-Negative Breast Cancer
Recruiting NCT06982521
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
PIK3CA Mutation · HER2- Negative Breast Cancer · Hormone Receptor Positive Tumor
Recruiting NCT04802759
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer
Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer
Not yet recruiting NCT07748260
De-escalation Neoadjuvant Therapy for Intermediate Risk HER2-positive Early Breast
HER2-positive Breast Cancer
Recruiting NCT06469606
Study on Female Patients' Mammographic Texture Features
Breast Cancer · Artificial Intelligence · Mammography
Not yet recruiting NCT07747623
One-level and Bi-level ESPB Application in Patients Undergoing Breast Surgery
Pain, Postoperative · Breast Surgery · Erector Spinae Plane Block
Recruiting NCT05812807
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
Anatomic Stage II Breast Cancer AJCC v8 · Early Stage Triple-Negative Breast Carcinoma · Anatomic Stage IIIA Breast Cancer AJCC v8
Recruiting NCT06106477
Impact of Intermittent Fasting on Biomarkers of Inflammation and Health-Related Quality of Life: A Feasibility Trial for Women With HR+/HER2- Early Breast Cancer
Breast Cancer
Recruiting NCT07214662
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-0587 as a Monotherapy and in Combination With Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive and Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer
Breast Cancer
Recruiting NCT07748598
HER2+ CNS Surveillance
Her 2 Positive Breast Cancer · Cancer · CNS
Recruiting NCT06065748
A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)
Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer
Recruiting NCT05318469
Ivermectin in Combination With Balstilimab or Pembrolizumab in Patients With Metastatic Triple Negative Breast Cancer
Anatomic Stage IV Breast Cancer AJCC v8 · Metastatic Triple-Negative Breast Carcinoma
Recruiting NCT05507879
TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer
Breast Carcinoma · Cardiomyopathy · Congestive Heart Failure
Recruiting NCT07748520
Effect of Nesting During Intramuscular Injection on Pain, Stress, and Breastfeeding Success in Cesarean-Born Term Newborns
Newborn Pain · Newborn Stress · Breastfeeding Success in Newborns
Recruiting NCT06658912
Planning Grant for TOPS for Breast Cancer Survivors
Breast Cancer · Weight Loss
Not yet recruiting NCT07552181
Phase II Trial of Pembrolizumab/Chemotherapy With Live Biotherapeutic Product MO-03 in Patients With Early Stage Triple Negative Breast Cancer
TNBC - Triple-Negative Breast Cancer · TNBC · Early Stage Triple-Negative Breast Carcinoma
Recruiting NCT07413939
RO7771950 Versus Tucatinib in Combination With Trastuzumab and Capecitabine in People With Locally Advanced or Metastatic Breast Cancer That is Human Epidermal Growth Factor Receptor 2 (HER2)-Positive
HER2-positive Breast Cancer
Not yet recruiting NCT07745517
Evaluating Interventions for Breast Cancer Screening in Ghana
Breast Cancer Screening
Recruiting NCT07078604
A Cancer Vaccine (STEMVAC) in Combination With Chemotherapy for the Treatment of PD-L1 Negative Metastatic Triple-Negative Breast Cancer
Anatomic Stage IV Breast Cancer AJCC v8 · Metastatic Triple-Negative Breast Carcinoma
Recruiting NCT05621564
Pre-operative Therapy in Breast Cancer
Breast Cancer
Recruiting NCT06748222
E-Mindfulness Approaches for Living After Breast Cancer
Breast Cancer · Depression
Recruiting NCT07739485
Paclitaxel Oral Solution in Triple Neagtive Breast Cancer Neoadjuvant Therapy: A Dose-Finding Study
Triple -Negative Breast Cancer
Recruiting NCT07017673
Phase II Trial of Ivonescimab in Combination With Carboplatin + Docetaxel in Patients With Early-Stage Triple Negative Breast Cancer
TNBC · TNBC - Triple-Negative Breast Cancer · Early Stage Triple-Negative Breast Carcinoma
Not yet recruiting NCT07517224
Assessing the Effect of an Aerobic Exercise Program on Vascular Function in Women With Non-Metastatic Breast Cancer
Breast Cancer Survivors
Not yet recruiting NCT07745257
Culmerciclib Plus Anlotinib and Endocrine Therapy for HR-Positive/HER2-Negative Metastatic Breast Cancer With Brain Metastases
HR-positive, HER2-negative Metastatic Breast Cancer With Brain Metastases
Recruiting NCT06123286
Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms
Breast Cancer · Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS) · Joint Pain
Recruiting NCT07743827
Olanzapine Based Dexamethasone-sparing Regimen for Breast Cancer Patients With Metabolic-risk Factors
Olanzapine · Breast Cancer · Dexamethasone
Not yet recruiting NCT07743632
Neoadjuvant Angiogenesis-Targeting Bispecific Chemoimmunotherapy for TNBC
Breast Cancer · Triple Negative Breast Cancer
Recruiting NCT06195306
Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction
Breast Atypical Hyperplasia · Breast Carcinoma · Breast Ductal Carcinoma In Situ
Recruiting NCT06552091
Guided Digital Self-Hypnosis Solution for Managing Hot Flashes in Patients Undergoing Adjuvant Hormone Therapy
Breast Cancer Female
Recruiting NCT07084558
ABCSG 61 / TEODOR : Neoadjuvant TrEatment Optimization Driven by Circulating Tumor DNA and endOcrine Responsiveness
Early and Locally Advanced Breast Cancer
Recruiting NCT05879926
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Breast Cancer
Not yet recruiting NCT07602868
A Comparative Study of Delayed Endoscopic DTI and Autologous Flap Reconstruction Post-Mastectomy
Breast Reconstruction After Mastectomy
Recruiting NCT06831838
A Randomized Controlled Trial (RCT) to Determine the Efficacy of a Multidisciplinary CBT Based Pain Management Program for the Treatment of Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS) in Breast Cancer Survivors
Breast Cancer
Recruiting NCT07739511
Paclitaxel Oral Solution in HER2-Positive Breast Cancer Neoadjuvant Therapy: A Dose-Finding Study
HER2 + Breast Cancer
Recruiting NCT07527741
A Study to Assess Treatment Patterns and Treatment Adherence in Early HER2-positive Breast Cancer Participants After Treatment Decentralization
Early-stage HER2+ Breast Cancer
Recruiting NCT07310420
A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With HR+, HER2- Advanced Breast Cancer
Advanced Breast Cancer
Recruiting NCT07744373
Tregs and miRNAs in Breast Milk: Effects on Infant Food Tolerance
Immune Tolerance · Food Tolerance
Recruiting NCT07743944
A Real-world Study Observing Treatment Patterns and Clinical Results for Patients in China With Hormone Receptor-positive, HER2-negative Metastatic Breast Cancer.
Breast Cancer
Enrolling by invitation NCT06680596
Detecting Tumor DNA in the Blood of HR+/HER2-low Metastatic Breast Cancer Patients to Find Candidates for T-DXd Therapy
Breast Cancer Metastatic · Breast Cancer Stage IV
Recruiting NCT05461768
A Study of BL-M07D1 in Patients With Locally Advanced or Metastatic HER2 Positive/Low Expression Breast Cancer and Other Solid Tumors
Breast Cancer · Locally Advanced or Metastatic Solid Tumor
Recruiting NCT07652242
Phase 1 Study of a Self-amplifying RNA Vaccine (ITI-5000) in Stage 2-3 Triple Negative Breast Cancer
Triple Negative Breast Cancer (TNBC)
Recruiting NCT06922708
Implementing Polygenic Risk Scores for Breast Cancer Prevention: a Feasibility Study
Breast Cancer
Not yet recruiting NCT07340619
Clinical Trial Evaluating the Biological Activity of a New Drug Identified as Prifetrastat (PF-07248144), Combined With Fulvestrant for the Treatment of Patients With Hormone Receptor Positive (HR+) and HER2 Negative (HER2-) Breast Cancer Extended to Other Organs.
Metastatic (Stage IV) Melanoma
Recruiting NCT07743294
Effect of Preoperative Rehabilitation Exercise on Improving Postoperative Lymphedema, Quality of Life and Care Needs in Patients With Breast Cancer Surgery
Breast Cancer and Rehabilitation