Autoimmune diseases

Recruiting NCT06865274☆ Save

Frequency of FCGR3A Gene Polymorphisms in Patients With Neuromyelitis Optica Spectrum Disorders, Anti-oligodendrocyte Myelin Protein Antibody Disease, and Multiple Sclerosis.

No phase Interventional Italy

Neuromyelitis Optica Spectrum Disorders · MOGAD · Multiple Sclerosis

Recruiting NCT06701968☆ Save

Effects of a Healthy Nordic Diet on Atherosclerosis in Patients with Coronary Heart Disease

No phase Interventional Sweden

Coronary Disease · Coronary Arteriosclerosis · Myocardial Infarction

Recruiting NCT06862843☆ Save

Study on Eating Habits and Association with "omic" Profiles in Families with a Subject Affected by a Chronic Immune-mediated Inflammatory Pathology. Observational Multicenter Study.

— Observational Italy

Juvenile Idiopathic Arthritis (JIA) · Crohn Disease (CD) · Ulcerative Colitis (UC)

Not yet recruiting NCT06859567☆ Save

Chester Step Test: is It Effective in Scleroderma Patients?

No phase Interventional Turkey (Türkiye)

Systemic Sclerosis (SSc) · Chester Step Test · 6 Minutes Walk Test

Recruiting NCT06606808☆ Save

Fluorescence Imaging of Risankizumab-800CW in Inflammatory Bowel Disease

Phase I / Phase II Interventional Netherlands

Ulcerative Colitis (UC) · Crohn Disease (CD)

Recruiting NCT06581042☆ Save

Study to Assess Treatment Patterns and Outcomes With Upadacitinib in Adult Participants With Inflammatory Bowel Disease in Belgium

— Observational Belgium

Ulcerative Colitis · Crohn's Disease

Recruiting NCT06816251☆ Save

A Phase II Clinical Study of HRS-1893 in Non-obstructive Hypertrophic Cardiomyopathy

Phase II Interventional China

Non-obstructive Hypertrophic Cardiomyopathy

Recruiting NCT00801333☆ Save

Derivation of Induced Pluripotent Stem Cells From an Existing Collection of Human Somatic Cells

— Observational Israel

Amyotrophic Lateral Sclerosis

Recruiting NCT06213857☆ Save

Beneficial Effect of Silymarin in Ulcerative Colitis

Phase II Interventional Egypt

Ulcerative Colitis

Not yet recruiting NCT06859931☆ Save

Clinical Trial of TQB3702 Tablets in Subjects With Systemic Lupus Erythematosus (SLE)

Phase II Interventional China

Systemic Lupus Erythematosus

Recruiting NCT05574387☆ Save

Metformin as Added on Therapy in Patients With Ulcerative Colitis

Phase II Interventional Egypt

Inflammatory Bowel Diseases

Not yet recruiting NCT06856265☆ Save

Efficacy of Mavacamten Combined With Radiofrequency Ablation in Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

No phase Interventional —

Obstructive Hypertrophic Cardiomyopathy · Mavacamten · Radiofrequency Ablation

Not yet recruiting NCT06856772☆ Save

Randomized Comparison of Morning Versus Bedtime Administration of Statins: A Cardiovascular Circadian Chronotherapy (C3) Trial

Phase IV Interventional Denmark

Cardiovascular Diseases (CVD) · Drug Effect · Atherosclerosis Cardiovascular Disease

Recruiting NCT05575505☆ Save

Phosphodiesterase Inhibitors, Pentoxifylline, as Adjunctive Therapy in Patients With Ulcerative Colitis.

Phase II Interventional Egypt

Inflammatory Bowel Diseases

Recruiting NCT05662293☆ Save

Characterization of Arrhythmia-induced Cardiomyopathy

— Observational Switzerland

Cardiomyopathy · Arrhythmia-induced Cardiomyopathy (AiCM)

Not yet recruiting NCT06857526☆ Save

The Relationship of Hand Sensory and Strength Assessments with Functionality and Kinesiophobia in Individuals with Rheumatoid Arthritis

— Observational —

Disease

Not yet recruiting NCT06855667☆ Save

Efficacy and Safety of Therapeutic Plasma Exchange vs Standard Medical Therapy in Severe Autoimmune Hepatitis.

No phase Interventional India

Autoimmune Hepatitis

Recruiting NCT06849882☆ Save

Dubousset Functional Test: an Investigation of Its Validity and Reliability in Individuals with Multiple Sclerosis

— Observational Turkey (Türkiye)

MS (Multiple Sclerosis)

Recruiting NCT06685744☆ Save

TeleNEURO-Rehabilitation Systems for Neurodegenerative Conditions: the FIT4TeleNEURO Pragmatic Trial

No phase Interventional Italy

Parkinson Disease · Multiple Sclerosis · Neurologic Diseases, General

Recruiting NCT06786390☆ Save

Improved Recovery of Walking in Acquired Muscle Weakness

No phase Interventional Italy

Critical Illness Myopathy · Critical Illness Polyneuropathy

Recruiting NCT04331639☆ Save

High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy

— Observational United States

Inflammatory Bowel Disease · Crohn Disease · Ulcerative Colitis

Recruiting NCT06834269☆ Save

Transcranial Static Magnetic Stimulation (tSMS) and Potential Theranostic Biomarkers in Amyotrophic Lateral Sclerosis.

No phase Interventional Italy

Amyotrophic Lateral Sclerosis (ALS)

Recruiting NCT06503237☆ Save

Safety and Efficacy of SWK002 in Patients With D2T-Rheumatoid Arthritis

No phase Interventional China

Rheumatoid Arthritis

Recruiting NCT06758024☆ Save

PROactive and Early Infliximab Monitoring and OPTimization in Inflammatory Bowel Disease

No phase Interventional Chile

Inflammatory Bowel Disease (IBD) · Crohn Disease (CD) · Ulcerative Colitis (UC)

Not yet recruiting NCT06852573☆ Save

Clinical Study of ZM001 Injection in the Treatment of Refractory Systemic Lupus Erythematosus

Phase I Interventional —

Systemic Lupus Erythematosus

Recruiting NCT05619588☆ Save

Exactech Vantage Total Ankle System Post Market Clinical Follow-Up - US Only

— Observational United States

Ankle Rheumatoid Arthritis · Arthritis of Ankle · Failure, Prosthesis

Recruiting NCT06224660☆ Save

Modulation of SERCA2a of Intra-Myocytic Calcium Trafficking in Cardiomyopathy Secondary to Duchenne Muscular Dystrophy

Phase I Interventional United States

DMD-Associated Dilated Cardiomyopathy

Recruiting NCT05479617☆ Save

Personalised Prediction of Disease Course in Ulcerative Colitis Using Multimodal Machine Learning - Part of the Presager Project

— Observational Denmark

Ulcerative Colitis

Recruiting NCT04699747☆ Save

Investigating the Utility of Demyelination Tracer [18F]3F4AP in Controls and Multiple Sclerosis Subjects

Phase I Interventional United States

Multiple Sclerosis

Recruiting NCT05691868☆ Save

Vantage Mobile Bearing Total Ankle System Post Market Clinical Follow-up (Outside US)

— Observational Spain, Switzerland

Rheumatoid Arthritis · Arthritis of Ankle · Failure, Prosthesis

Enrolling by invitation NCT06849960☆ Save

Relıabılıty and valıdıty of the Two-minute Test wıth Multiple Sclerosis

— Observational Turkey (Türkiye)

Multiple Sclerosis

Not yet recruiting NCT06848283☆ Save

Randomized Controlled Trial on Carotid Atherosclerosis Screening in Asymptomatic Smokers and Hypertensive Adults: Prevalence and Impact on Cardiovascular Prevention

No phase Interventional —

Carotid Artery Atheroma · Cardiovascular Risk Stratification

Not yet recruiting NCT06847607☆ Save

A Multicenter Prospective Study of Iptacopan in the Treatment of Refractory/Relapsed Autoimmune Hemolytic Anemia (AIHA)

No phase Interventional China

AIHA - Warm Autoimmune Hemolytic Anemia · AIHA - Cold Autoimmune Hemolytic Anemia

Recruiting NCT06838884☆ Save

An Alternative Assessment in Patients with Rheumatoid Arthritis: 6 Minute Step Test

No phase Interventional Turkey (Türkiye)

Rheumatoid Arthritis (RA · 6 Minutes Stepper Test

Recruiting NCT05682482☆ Save

LT4/LT3 Combination Therapy Versus LT4 Monotherapy in Patients with Autoimmune Hypothyroidism.

Phase III Interventional Netherlands

Autoimmune Hypothyroidism

Recruiting NCT04970446☆ Save

Microbial Restoration in Inflammatory Bowel Diseases

Phase I / Phase II Interventional Australia

Fecal Microbiota Transplantation · Crohn Disease · Inflammatory Bowel Diseases

Recruiting NCT06718920☆ Save

Adverse Childhood Experiences in Patients With MS: Impact on Quality of Life and on Coping Strategies Towards the Disease and Its Treatment

— Observational Italy

Multiple Sclerosis

Not yet recruiting NCT06755021☆ Save

Whey Protein Milk-Derived Exosomes

No phase Interventional —

Ulcerative Colitis · Inflammatory Bowel Disease

Not yet recruiting NCT06844799☆ Save

A Study of HS-20137 in Participants with Moderate-to-severe Plaque Psoriasis

Phase III Interventional —

Moderate-to-severe Plaque Psoriasis

Recruiting NCT06764563☆ Save

The Effect of a Mediterranean Diet on Quality of Life in Multiple Sclerosis Patients

No phase Interventional Israel

Multiple Sclerosis

Recruiting NCT06845722☆ Save

Combined Effects of Balance and Cognitive Training in Patients With Multiple Sclerosis

No phase Interventional Pakistan

Multiple Sclerosis

Not yet recruiting NCT06842810☆ Save

Fibroblast Growth Factor 21 in Systemic Lupus Erythematosus

— Observational —

Systemic Lupus Erthematosus

Not yet recruiting NCT06838624☆ Save

RedCord in Neurogenic Bowel Dysfunction in Multiple Sclerosis

No phase Interventional Spain

Multiple Sclerosis · Pelvic Floor Disorder

Recruiting NCT06735053☆ Save

Impact of Virtual Reality Physiotherapy on Multiple Sclerosis Patients

No phase Interventional Spain

Multiple Sclerosis

Recruiting NCT06129214☆ Save

Partial Synovectomy in Articular Side of Quadriceps Tendon Verified to Reduce Crepitus in Retrospective Study

No phase Interventional South Korea

Osteoarthritis, Knee · Rheumatoid Arthritis, Knee · Spontaneous Osteonecrosis of Knee

Recruiting NCT06608797☆ Save

Testing the Feasibility of Computer-based Cognitive Training in Individuals with Multiple Sclerosis Living in the Community

No phase Interventional United States

Multiple Sclerosis

Recruiting NCT06841042☆ Save

A Study of SCTB35 in Patients with Systemic Lupus Erythematosus

Phase I / Phase II Interventional China

System Lupus Erythematosus

Not yet recruiting NCT06837558☆ Save

Predictors of Bone Mineral Density in Lupus Nephritis Activity

— Observational —

Bone Mineral Density and Lupus Nephritis Activity

Recruiting NCT06830187☆ Save

Investigating the Relationship Between Temporal Bone CT, Bone Density, and Hearing Loss in Otosclerosis Patients

— Observational Turkey (Türkiye)

Otosclerosis of Middle Ear · Bone Density · Vitamin D Deficiency

Not yet recruiting NCT06834776☆ Save

Evaluation of Neuromuscular Blockade Responses in Statin-Using and Non-Using Patients

— Observational —

Neuromuscular Blockade · Statin-Associated Myopathy · Neuromuscular Monitoring

Not yet recruiting NCT06740656☆ Save

Neuromuscular Complications of MEK Inhibitors: a French Case Series and a Systematic Review of the Literature

— Observational France

Myositis · Myasthaenia Gravis · Neuropathy

Recruiting NCT02486562☆ Save

IConquerMS™ - a Patient-Powered Research Network for Multiple Sclerosis

— Observational United States

Multiple Sclerosis

Not yet recruiting NCT06833307☆ Save

The Efficacy and Safety of SHR-1314 in the Treatment of Pediatric Patients of Age 6 to <18 Years With Moderate to Severe Plaque Psoriasis

Phase III Interventional China

Children and Adolescents Aged 6 to 18 With Moderate-to-Severe Plaque Psoriasis

Recruiting NCT06833541☆ Save

Research on Gut Microbiota and Metabolomics in Diabetic Kidney Disease

— Observational China

Diabetic Nephropathy Type 2 · Type 2 Diabetes Mellitus (T2DM) · Chronic Kidney Disease

Recruiting NCT06833450☆ Save

Reliability of IUS in Crohn's Disease

No phase Interventional France

Crohn Disease (CD)

Recruiting NCT06833489☆ Save

Transcriptomic Analysis to Put an End to Misdiagnosis in Patients With Rare Muscle Diseases

No phase Interventional France

Rare Genetic Muscle Diseases · Muscular Dystrophy, Duchenne · Muscular Dystrophy, Becker

Recruiting NCT06819826☆ Save

A Study of SC0062 Capsule for the Treatment of IgA Nephropathy with Proteinuria

Phase III Interventional China

IgA Nephropathy (IgAN)

Not yet recruiting NCT06720961☆ Save

The Microbial Impact on Intestinal Fibrosis and the Associated Immune Microenvironment in Crohn's Disease

— Observational Italy

Crohn Disease (CD)

Recruiting NCT06827834☆ Save

Spinal Cord Monitoring in Multiple Sclerosis

— Observational Netherlands

Multiple Sclerosis

Not yet recruiting NCT06827587☆ Save

Efficacy and Safety of Efgartigimod Sequential Therapy with Telitacicept in Generalized Myasthenia Gravis

No phase Interventional —

Myasthenia Gravis · Autoimmune Diseases · Neuromuscular Diseases

Recruiting NCT06477536☆ Save

Long-Term Safety and Efficacy of HB0034 in Subjects With Generalized Pustular Psoriasis

Phase II / Phase III Interventional China

Generalized Pustular Psoriasis

Recruiting NCT06826638☆ Save

Unraveling Active Ingredients of Neurorehabilitation: Investigating Cortical Activity During Task-oriented Exercises

— Observational Italy

Multiple Sclerosis · Healthy Volunteer

Recruiting NCT02719314☆ Save

Glucocorticoid-induced Osteoporosis in Patients With Chronic Inflammatory Rheumatic Diseases or Psoriasis

— Observational Germany

Osteoporosis · Inflammatory Rheumatism

Recruiting NCT06723444☆ Save

Improving Learning and Memory in Portuguese Patients With Multiple Sclerosis

No phase Interventional Portugal

Multiple Sclerosis

Recruiting NCT06820008☆ Save

Measurement and Impact of Physical Impairment in Amyotrophic Lateral Sclerosis: Use of Digital Technologies - A Precision ALS Project

— Observational Ireland

Amyotrophic Lateral Sclerosis · Motor Neurone Disease

Recruiting NCT05914155☆ Save

Clinical Study of Rituximab for the Treatment for Idiopathic Membranous Nephropathy with Nephrotic Syndrome

Phase III Interventional Japan

Glomerulonephritis, Membranous · Nephrotic Syndrome，Idiopathic

Recruiting NCT06820125☆ Save

Isolated Versus Combined Cognitive and Motor High-tech Rehabilitation

No phase Interventional Italy

Rehabilitation · Multiple Sclerosis · Cognitive Deficit

Recruiting NCT06769386☆ Save

Investigation of Muscle Oxygenation in Patients With Rheumatoid Arthritis

— Observational Turkey (Türkiye)

Rheumatoid Arthritis

Not yet recruiting NCT06819358☆ Save

Individualized Functional Imaging-Guided Repetitive Transcranial Magnetic Stimulation (rTMS) for Treating Postural Gait Disorders in Patients with Amyotrophic Lateral Sclerosis (ALS): a Randomized, Crossover, Controlled, Double-Blind Clinical Study

Early Phase I Interventional —

Amyotrophic Lateral Sclerosis (ALS)

Recruiting NCT06375005☆ Save

Efficacy and Safety of Telitacicept in the Treatment of Systemic Sclerosis

Phase II Interventional China

Diffuse Cutaneous Systemic Sclerosis

Not yet recruiting NCT06815224☆ Save

The Role of Perirenal Fat As Predictor in Diabetic Nephropathy

— Observational —

Diabetic

Recruiting NCT05416385☆ Save

Carotid Intraplaque Neovascularization Combined With Stress Echo

— Observational Canada

Atherosclerosis · Cardiovascular Diseases · Acute Coronary Syndrome

Recruiting NCT06228924☆ Save

Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC

Phase I Interventional United States

Arrhythmogenic Right Ventricular Cardiomyopathy

Recruiting NCT06067698☆ Save

Alpha Lipoic Acid in Ulcerative Colitis

No phase Interventional Egypt

Ulcerative Colitis · Ulcerative Colitis (UC)

Not yet recruiting NCT06811558☆ Save

Ixekizumab Versus Secukizumab in Over 70-year-old Patients with Psoriasis

No phase Interventional —

Over 70-year-old Patients with Psoriasis

Not yet recruiting NCT06810154☆ Save

Multi-strain Probiotics to Prevent Necrotizing Enterocolitis in Very Preterm Infants

Phase III Interventional Canada

Necrotizing Enterocolitis (NEC)

Recruiting NCT06810219☆ Save

Augmented Reality BCI Longitudinal Study for Persons With Late Stage ALS

No phase Interventional United States

ALS (Amyotrophic Lateral Sclerosis)

Not yet recruiting NCT06581029☆ Save

Evaluating Mental Health Challenges in Juvenile Lupus Erythematosus and Their Caregivers

— Observational —

SLE

Recruiting NCT04320680☆ Save

Systemic Lupus Erythematosus Within the Framework of the Multidisciplinary Consultation

No phase Interventional France

Systemic Lupus Erythematosus

Recruiting NCT06805448☆ Save

Intraglandular Treatment With Adipose-derived Mesenchymal Stem Cells in Patients With Xerostomia Due to Sjögren's Disease

Phase I / Phase II Interventional Denmark

Sjorgren&#39;s Syndrome

Not yet recruiting NCT06805643☆ Save

Dixon MRI Imaging Histology for Predicting Postoperative Infection in Posterior Lumbar Fusion for Myasthenia Gravis

— Observational —

Lumbar Vertebrae · Surgical Site Infection · Radiomics

Recruiting NCT06802887☆ Save

Long-term Treatment With Ustekinumab in Patients With Crohn's Disease and Ulcerative Colitis: a Cohort Study

— Observational Italy

IBD - Inflammatory Bowel Disease

Not yet recruiting NCT06802848☆ Save

Real-World Study of Xeligekimab for Moderate to Severe Plaque Psoriasis(XP-Real)

— Observational China

Plaque Psoriasis · Psoriatic Arthritis · Scalp Psoriasis

Not yet recruiting NCT06801028☆ Save

Efficacy of Injection Sekucinumab in Erythrodermic Psoriasis

— Observational Pakistan

Erythrodermic Psoriasis

Recruiting NCT06688396☆ Save

Dilated Cardiomyopathy Detection Using AI and Screening With Mobile Technology (DCM-DETECT)

No phase Interventional United States

Dilated Cardiomyopathy · Heart Failure · Heart Disease

Recruiting NCT05636709☆ Save

National GMA Post-market Clinical Follow-up Study (GRACE)

— Observational Spain

Crohn Disease · Ulcerative Colitis

Recruiting NCT06800326☆ Save

Diagnostic Concordance of MR Enterography and Ultrasound for Treatment Response Assessment in Crohn's Disease (MANTRA)

— Observational United Kingdom

Crohn Disease

Recruiting NCT06396260☆ Save

Structural and Functional Networks in ALS: An Insight Into Pseudobulbar Affect

No phase Interventional Denmark

Amyotrophic Lateral Sclerosis · Pseudobulbar Affect

Recruiting NCT05852418☆ Save

Registry Study of Assistive Devices, Medicines and Healthcare Measures in ALS, SMA and Other Neurological Diseases.

— Observational Germany

Amyotrophic Lateral Sclerosis

Recruiting NCT06029257☆ Save

A Study of Tildrakizumab in the Treatment of Genital Psoriasis (CZATCH-Genital-PsO)

— Observational Austria

Genital Psoriasis

Recruiting NCT06030076☆ Save

A Study to Assess the Effects of Switching From a Biologic Treatment to Tildrakizumab Using Patient-reported Outcomes in Adult Participants With Moderate to Severe Plaque Psoriasis

— Observational Austria

Plaque Psoriasis

Not yet recruiting NCT06784076☆ Save

Establishing the Salience of Type 1 Interferon Pathway Blockade in the Central Mechanisms of SLE Related Fatigue

— Observational —

Systemic Lupus Erythematosus

Not yet recruiting NCT05105958☆ Save

Tideglusib for the Treatment of Amyotrophic Lateral Sclerosis

Phase II Interventional Switzerland

Amyotrophic Lateral Sclerosis

Recruiting NCT06796569☆ Save

Systemic Immune Inflammatory Index in Systemic Lupus Erythematosus

— Observational Egypt

Systemic Lupus Erythematosus · Lupus Nephritis

Recruiting NCT02103361☆ Save

Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project

— Observational United States

Psoriasis · Pregnancy · Psoriatic Arthritis

Not yet recruiting NCT06147232☆ Save

Prevention of Chronic Kidney Disease(CDK) Progression in Type 1 Diabetes With Long Term Use of Sodium-Glucose-coTransporter Inhibitors Avoiding Kidney hypOxia

Phase II Interventional Denmark, United Kingdom

Nephropathy · Diabetic Nephropathies · Diabetes Mellitus, Type 1

Not yet recruiting NCT06794671☆ Save

A Basket Trial of Vunakizumab in Inflammatory Skin Diseases

— Observational —

Inflammatory Skin Diseases · Psoriasis

Recruiting NCT06794684☆ Save

PRogression of Atheroma Evaluated by CT Angiography and IntraCoronary Imaging tEchniques

— Observational China

Coronary Arterial Disease (CAD) · Coronary Arteriosclerosis

Recruiting NCT06793020☆ Save

Diagnosis, Treatment, and Outcome Assessment of Septic Cardiomyopathy Using an Integrated Mathematical Model

— Observational Lithuania, Poland

Septic Cardiomyopathy

Not yet recruiting NCT06794710☆ Save

Early Identification and Treatment of Rare Cardiomyopathy Cohorts

No phase Interventional China

Hypertrophic Cardiomyopathy (HCM) · Dilated Cardiomyopathy (DCM) · Metabolic Cardiomyopathy