Autoimmune diseases

Recruiting NCT05089227☆ Save

Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Autoimmune Hemolytic Anemia: a Prospective, Phase II, Randomized, Multicenter Study

Phase II Interventional France

Prolonged Anticoagulation · Venous Thromboembolic Disease · Autoimmune Hemolytic Anemia

Recruiting NCT05505500☆ Save

Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome.

— Observational United States

Fluid Overload · Glomerulosclerosis, Focal Segmental · Edema

Not yet recruiting NCT04768777☆ Save

Behavioral Intervention for Physical Activity and Sexual Dysfunction in Multiple Sclerosis

No phase Interventional United States

Multiple Sclerosis, Relapsing-Remitting · Sexual Dysfunction

Recruiting NCT07277257☆ Save

Evaluating a New Therapy for Dry Eye in Patients With Sjögren's Syndrome

Phase IV Interventional United States

Sjogren Syndrome With Keratoconjunctivitis

Recruiting NCT06435468☆ Save

Biocollection of Rare Pediatric-onset of Autoimmune and Autoinflammatory Diseases

No phase Interventional France

Systemic Lupus · Autoimmune Diseases · Autoinflammatory Disease

Recruiting NCT07265284☆ Save

A Study to Evaluate Efficacy and Safety of IBI112 in Adolescent Participants With Moderate to Severe Plaque Psoriasis

Phase III Interventional China

Psoriasis

Not yet recruiting NCT07295834☆ Save

Modafinil For Fatigue in IBD: A Feasibility Randomised Controlled Trial

Phase II Interventional United Kingdom

Crohn Disease (CD) · Ulcerative Colitis (UC) · Fatigue

Recruiting NCT07258745☆ Save

Pharmacokinetic, Safety, Tolerability, and Immunogenicity Comparison of CKD-704 (Risankizumab Biosimilar), With EU-approved Skyrizi®, and US-licensed Skyrizi® in Healthy Adult Participants

Phase I Interventional Poland

Psoriasis

Recruiting NCT06235580☆ Save

Genotype-phenotype Characterization Study on Genetic Diseases With Immune and Neurological Dysfunctions

— Observational France

Genetic Diseases · Immune Dysfunction · Neurological Disease

Recruiting NCT06982352☆ Save

Safety and Pharmacokinetics of LPX-TI641 in Atopic Dermatitis and Psoriasis

Phase I Interventional United States, Jordan

Atopic Dermatitis (AD) · Psoriasis (PsO)

Enrolling by invitation NCT07295613☆ Save

ReGistry of hypeRtrophic cArDIomyopathy: Regional fEatures, geNeTics and Course

— Observational Russia

Hypertrophic Cardiomyopathy (HCM)

Not yet recruiting NCT07294495☆ Save

Effect of Henagliflozin on Myocardial Fibrosis in Non-Obstructive HCM: A Randomized, Double-Blind, Placebo-Controlled Trial Using 68Ga/18F-FAPI PET/CMR

No phase Interventional China

HCM - Hypertrophic Cardiomyopathy

Recruiting NCT07293988☆ Save

Spastic Myopathy in Adults With Cerebral Palsy

No phase Interventional France

Cerebral Palsy (CP)

Recruiting NCT05201469☆ Save

VIBRANT: VIB4920 for Active Lupus Nephritis

Phase II Interventional United States

Lupus Nephritis

Recruiting NCT07293338☆ Save

Prognostic Values of Coronary Microvascular Dysfunction in Patients With Dilated Cardiomyopathy

— Observational China

Dilated Cardiomyopathy (DCM)

Enrolling by invitation NCT06708000☆ Save

Personalized Evaluation of Susptected Myocardial Ischemia

Phase III Interventional Denmark

Chronic Coronary Syndrome · Angina Pectoris · Coronary Artery Disease

Recruiting NCT07264101☆ Save

Validity And Reliability Of The Four Square Step Test In Individuals With Rheumatoid Arthritis

— Observational Turkey (Türkiye)

Rheumatoid Arthritis (RA)

Not yet recruiting NCT07291375☆ Save

Role of Amlodipine in Reduction of CIN

Early Phase I Interventional —

Contrast-induced Nephropathy

Not yet recruiting NCT07292116☆ Save

Disease Progression in ms

— Observational —

Prediction of Disease Progression · Multiple Sclerosis

Recruiting NCT07292961☆ Save

Investigating the Effectiveness of the Biopsychosocial Model-Based Exercise Approach in Children and Adults Diagnosed With Scleroderma

No phase Interventional Turkey (Türkiye)

Scleroderma · Scleroderma, Localized · Scleroderma Systemic

Recruiting NCT06865105☆ Save

Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis

Phase II Interventional United States, Canada +4

Psoriatic Arthritis

Not yet recruiting NCT07292454☆ Save

Prevalence of Helicobacter Pylori on Patients With Chronic Inflammatory Bowel Disease (IBD) at the CHU of Guadeloupe

— Observational Guadeloupe

HELICOBACTER PYLORI INFECTIONS · Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis)

Recruiting NCT07292545☆ Save

Video-Based Proprioceptive Exercise Program in ALS

No phase Interventional Turkey (Türkiye)

Amyotrophic Lateral Sclerosis

Recruiting NCT02915198☆ Save

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

Phase IV Interventional United States

Prediabetic State · Atherosclerosis · Metformin

Recruiting NCT07289399☆ Save

Is There a Benefit From Addition of Treadmill Walking to Diet Restriction in Psoriasis Women With PCOS?

No phase Interventional Egypt

Psoriasis · Polycystic Ovary Syndrome

Not yet recruiting NCT07287930☆ Save

A Study of YTS109 Cell in Subjects With Relapsed/Refractory Autoimmune Hemolytic Anemia

Phase I Interventional —

Autoimmune Hemolytic Anemia

Recruiting NCT06472336☆ Save

IntraCranial Atherosclerosis Related Large-vessel Occlusion Treated With Urgent Stenting (ICARUS)

No phase Interventional Switzerland

Stroke · Stroke, Acute Ischemic · Intracranial Atherosclerosis

Recruiting NCT07269223☆ Save

Oral Vitamin D3 Effect on Inflammatory Biomarkers in Ulcerative Colitis Patients

No phase Interventional Pakistan

Ulcerative Colitis (UC)

Recruiting NCT07175493☆ Save

A Study of CM336 in Patients With Relapsed or Refractory Autoimmune Cytopenia

Phase I / Phase II Interventional China

Autoimmune Cytopenia · Immune Thrombocytopenia (ITP) · Autoimmune Hemolytic Anemia

Recruiting NCT05488431☆ Save

Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)

Phase II Interventional United States

Dyslipidemias · Cardiovascular Diseases · HIV Infections

Recruiting NCT06182969☆ Save

A Study of APG-2575 in Patients With Mild-to-moderate Systemic Lupus Erythematosus.

Phase I / Phase II Interventional China

SLE

Recruiting NCT07219537☆ Save

A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule

No phase Interventional United States

Lynch Syndrome · Crohn Disease · Inflammatory Bowel Diseases

Recruiting NCT05116943☆ Save

Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative Disorders

— Observational United States

Amyotrophic Lateral Sclerosis

Recruiting NCT07235904☆ Save

Efficacy of Top-down Therapy With Mirikizumab Versus Standard of Care With Azathioprine in Patients With Newly Diagnosed Moderate-to-severe Ulcerative Colitis

Phase IV Interventional Germany

Ulcerative Colitis (UC)

Recruiting NCT04982419☆ Save

Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial

Phase II / Phase III Interventional United States

Acute Kidney Injury · Heart Failure · Contrast Induced Nephropathy

Enrolling by invitation NCT04520347☆ Save

IVTCC 2.0: A Prospective Multicenter Ventricular Tachycardia Catheter Ablation Registry

— Observational United States, Canada +5

Ventricular Arrhythmia · Ventricular Tachycardia · Premature Ventricular Contraction (PVC)

Recruiting NCT00692939☆ Save

Autologous Stem Cell Transplantation for Crohn's Disease

Phase I / Phase II Interventional United States

Crohn's Disease

Recruiting NCT07006493☆ Save

REFINE-HCM: Intramyocardial Septal Radiofrequency Ablation for Obstructive Hypertrophic Cardiomyopathy

No phase Interventional China

Hypertrophic Cardiomyopathy, Obstructive

Recruiting NCT05603728☆ Save

Exactech Shoulder Post Market Clinical Follow-up Study

— Observational United States, Canada +3

Osteo Arthritis Shoulders · Osteonecrosis · Rotator Cuff Tears

Recruiting NCT01962415☆ Save

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

Phase II Interventional United States

Primary Immunodeficiency (PID) · Congenital Bone Marrow Failure Syndromes · Inherited Metabolic Disorders (IMD)

Recruiting NCT06280755☆ Save

Clinical Impact Through AI-assisted MS Care - A Retrospective Multi-center Observational Study.

— Observational Czechia, Germany

Multiple Sclerosis · NMO Spectrum Disorder · Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease

Recruiting NCT06742008☆ Save

Assessment of the Predictive Value of Anti-beta1AR and Anti-L-CaC Antibodies in the Evolution to Dilated Cardiomyopathy in Patients With Acute Viral Myocarditis

— Observational China

Viral Myocarditis

Recruiting NCT07130929☆ Save

Functional Electrical Stimulation to Treat Critical Neuromyopathy After Severe Stroke: a Pilot Study.

No phase Interventional Italy

Intensive Care Unit (ICU) Acquired Weakness (ICU - AW) · Acquired Brain Injury (Including Stroke)

Not yet recruiting NCT07274124☆ Save

Pain Neuroscience Education and Vagus Nerve Stimulation on Recovery in Individuals With Rheumatoid Arthritis

No phase Interventional Turkey (Türkiye)

Rheumatic Diseases · Rheumatoid Arthritis (RA)

Recruiting NCT06721962☆ Save

Treatment of Moderate to Severe Refractory Crohn's Disease

Phase I / Phase II Interventional United States

Crohns Disease

Recruiting NCT07095075☆ Save

A Study of LUCAR-DKS1 in Subjects With Relapsed/Refractory Autoimmune Diseases

Early Phase I Interventional China

Relapsed/Refractory Autoimmune Diseases

Recruiting NCT06579443☆ Save

Robotic Inflammatory Bowel Disease Development, Learning and Efficacy Study

— Observational United Kingdom

Inflammatory Bowel Diseases · Crohn Disease · Ulcerative Colitis

Recruiting NCT05633875☆ Save

Multimodal Imaging Signatures of the Biological Mechanisms Underlying Neurodegeneration in Multiple Sclerosis

— Observational France

Multiple Sclerosis (MS)

Not yet recruiting NCT07272850☆ Save

Comparison Between JAK Inhibitors and Traditional Treatment of Rheumatoid Arthritis

— Observational —

Rheumatoid Arthritis · Arthritis

Recruiting NCT07115862☆ Save

Effects of Pomegranate Juice on Ulcerative Colitis

No phase Interventional United States

Ulcerative Colitis (Disorder)

Recruiting NCT07130604☆ Save

Evaluate the Efficacy and Safety of D-2570 in Subjects With Moderate to Severe Plaque Psoriasis

Phase III Interventional China

Plaque Psoriasis

Not yet recruiting NCT07273292☆ Save

Autonomic Dysfunction in Neuromyelitis Optica Spectrum Disorder and Multiple Sclerosis : A Comparative Study

— Observational —

NMO and MS

Not yet recruiting NCT06590090☆ Save

Natrunix in Combination With Methotrexate for Rheumatoid Arthritis Treatment

Phase II Interventional —

Rheumatoid Arthritis

Recruiting NCT05713890☆ Save

Home-based Action Observation Treatment With Virtual-reality for Arm Rehabilitation in People With Multiple Sclerosis

No phase Interventional Italy

Multiple Sclerosis

Enrolling by invitation NCT07032246☆ Save

Clinical Impact Through AI-assisted MS Care - A Prospective Multi-center Study

No phase Interventional Czechia, Germany +1

Multiple Sclerosis · Radiologically Isolated Syndrome · Clinically Isolated Syndrome

Recruiting NCT04745728☆ Save

Different Immunosuppressive Treatment in iMN

Phase III Interventional China

Idiopathic Membranous Nephropathy

Not yet recruiting NCT07256470☆ Save

Salivary Replication of BK Virus in Post-kidney Transplant

No phase Interventional France

BK Virus · Salivary Replication · Kidney Transplantation

Recruiting NCT07100873☆ Save

A Phase 1 Study of ADI-001 in Rheumatoid Arthritis

Phase I Interventional China

Rheumatoid Arthritis (RA)

Not yet recruiting NCT06373263☆ Save

Evaluating Tools to Communicate Scleroderma Research Results to Patients - Trial #1

No phase Interventional —

Scleroderma · Systemic Sclerosis

Recruiting NCT07268833☆ Save

Translating Single-cell Vulnerability Into Novel ALS Biomarkers and Therapeutic Targets: Towards a Liquid Nerve Biopsy

— Observational Italy

Amyotrophic Lateral Sclerosis (ALS) · Peripheral Neuropathies

Not yet recruiting NCT07270120☆ Save

Senolytics for Secondary Progressive MS

Phase I Interventional United States

Multiple Sclerosis (MS) Secondary Progressive

Recruiting NCT00747851☆ Save

NETs: Protection or Harm in Neonatal Inflammation or Infection

— Observational United States

Necrotizing Enterocolitis (NEC)

Recruiting NCT04882904☆ Save

Continuous Measurement of Activity in Patients With Muscle Pathology and in Control Subjects. ActiSLA Part.

No phase Interventional Belgium

Amyotrophic Lateral Sclerosis

Not yet recruiting NCT07266220☆ Save

Carotid Doppler Screening for Subclinical Atherosclerosis in Diabetic CKD Patients.

— Observational —

Diabetes Mellitus, Type 2 · Chronic Kidney Disease · Atherosclerosis

Recruiting NCT03248284☆ Save

Immune-Competent Cell Manifestations in Psoriatic Arthritis Achilles Tendons

— Observational Denmark

Psoriatic Arthritis · Enthesitis

Not yet recruiting NCT07233382☆ Save

Assessing the Efficacy of Probiotics in Prevention of NEC in Preterm Babies

No phase Interventional —

NEC · NEC - Necrotizing Enterocolitis

Recruiting NCT06368518☆ Save

Austrian Hypertrophic Cardiomyopathy Registry

— Observational Austria

Hypertrophic Cardiomyopathy

Recruiting NCT04924270☆ Save

Safety and Efficacy of Capsule FMT in Treatment-naïve Patients With Newly Diagnosed Chronic Inflammatory Diseases

Phase II Interventional Denmark

Rheumatoid Arthritis · Ankylosing Spondylitis · Psoriatic Arthritis

Recruiting NCT07265999☆ Save

Severity Factors of Dermatomyositis in the Caribbean Population - DM-ANTILLES

— Observational Guadeloupe

Dermatomyositis

Not yet recruiting NCT07263607☆ Save

A Multicenter Clinical Trial Evaluating the Efficacy and Safety of Taurine as an Adjunctive Therapy in Multiple Sclerosis

Phase II Interventional —

Multiple Sclerosis (MS) Relapsing Remitting

Recruiting NCT07263204☆ Save

AI-Enabled Diagnosis and Prognosis of Hypertrophic Cardiomyopathy

— Observational China

Hypertrophic Cardiomyopathy (HCM) · Left Ventricular Hypertrophy

Not yet recruiting NCT07263880☆ Save

Clostridium Butyricum in Stenosing Crohn's Desease

Phase I / Phase II Interventional Italy

Crohn Disease (CD)

Recruiting NCT05955066☆ Save

Effect of JAK Inhibitor on Erosion Healing in RA

Phase IV Interventional Hong Kong

Rheumatoid Arthritis

Recruiting NCT05895981☆ Save

Exploratory Clinical Trial of Safety and Efficacy of Sacral Nerve Stimulation in Patients With Ulcerative Colitis.

No phase Interventional China

Ulcerative Colitis

Recruiting NCT07159789☆ Save

Repetitive Transcranial Magnetic Stimulation (rTMS) in MS Induced Spastic Paraparesis

No phase Interventional Canada

Multiple Sclerosis

Not yet recruiting NCT07265206☆ Save

A Study of HY001N in the Treatment of Relapsed or Refractory Neurological Autoimmune Diseases

Early Phase I Interventional —

Neurological Autoimmune Diseases

Enrolling by invitation NCT07248891☆ Save

Type 2 Diabetes and Associated Factors in Mexico

— Observational Mexico

Diabetes Mellitus, Type 2 · Chronic Kidney Disease · Diabetic Nephropathy

Recruiting NCT06256575☆ Save

Study of Diosmin for the Treatment of Digital Ulcers in Systemic Sclerosis

No phase Interventional Canada

Scleroderma, Systemic · Digital Ulcer

Not yet recruiting NCT07251179☆ Save

Characterization of Autoreactive b Lymphocytes in Autoimmune Diseases and Immune Deficiencies

— Observational France

Systemic Lupus Erythematosus · Systemic Scleroderma · ANCA-associated Vasculitis

Not yet recruiting NCT05179577☆ Save

A Study to Investigate Arbaclofen ER Tablets for the Treatment of Spasticity in Patients With Multiple Sclerosis

Phase III Interventional —

Spasticity

Recruiting NCT07261306☆ Save

Comparison Between Oral Methotrexate and Tofacitinib in Chronic Plaque Psoriasis

Early Phase I Interventional Pakistan

Psoriasis

Recruiting NCT03642795☆ Save

Validation of the French Version of the CQR (Compliance Questionnaire Rheumatology)

— Observational France

Rheumatoid Polyarthritis

Recruiting NCT07261826☆ Save

Real-World Study on Fecal Microbiota Transplantation: Long-Term Effectiveness and Safety Statistics

— Observational China

Clostridium Difficile Infection Recurrence · Ulcerative Colitis (UC) · Crohn Disease (CD)

Not yet recruiting NCT07262112☆ Save

Efficacy of Resistance Exercise and an Anti-Inflammatory Diet on Pain, Disease Activity, Functional Status, and Quality of Life in Patients With Rheumatoid Arthritis

No phase Interventional —

Rheumatoid Arthritis

Recruiting NCT06363357☆ Save

The Effect of a Muscle-mimicking, Fabric-type Shoulder Orthosis on Functional Movements of the Upper Limb in Patients With Neuromuscular Disorder

No phase Interventional South Korea

Muscular Dystrophy, Duchenne · Orthotic Devices · Upper Extremity

Recruiting NCT06815133☆ Save

Effectiveness and Safety of Zilucoplan Treatment for French Patients With Myasthenia Gravis Over 3 Months

— Observational France

Myasthenia Gravis

Not yet recruiting NCT07262359☆ Save

Intravascular Imaging Evaluated Calcified Nodule China Registry

— Observational —

Coronary Artery Disease · Coronary Artery Atherosclerosis · Coronary Calcified Nodules

Not yet recruiting NCT07251556☆ Save

GLP-1 Receptor Agonists in Non-diabetic Patients With Psoriatic Arthritis

Phase IV Interventional —

Psoriasis Arthritis

Recruiting NCT02567136☆ Save

Imaging Biomarkers in ALS

— Observational United States

Amyotrophic Lateral Sclerosis · Primary Lateral Sclerosis

Not yet recruiting NCT07257900☆ Save

Comparison of Structured Exercise and Exergaming in Pediatric-Onset Multiple Sclerosis

No phase Interventional —

Pediatric-Onset Multiple Sclerosis (POMS) · Exercise Training

Recruiting NCT07233291☆ Save

A Pilot Study to Assess How Safe and Effective Oral Roflumilast is for Treating Moderate to Severe Psoriasis in Adults

Phase II Interventional Egypt

Psoriasis (PsO)

Enrolling by invitation NCT05021029☆ Save

UC Davis Cohort of Pre-Malignant and Malignant Gastro-Intestinal DisEases Study

— Observational United States

Intestinal Metaplasia · Chronic Gastritis · Atrophic Gastritis

Enrolling by invitation NCT07257588☆ Save

The Efficacy of Hyperbaric Oxygen-assisted Treatment for ASUC and Refractory IBD

No phase Interventional China

Ulcerative Colitis

Not yet recruiting NCT07252271☆ Save

Very Low Dose Prednisolone on Newly Diagnosed Rheumatoid Arthritis

Phase IV Interventional —

Rhematoid Arthritis

Recruiting NCT06094205☆ Save

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02)

No phase Interventional United States

Anarthria · Dysarthria · Tetraplegia

Recruiting NCT06661876☆ Save

Cardiac RadiothErapy For hEart faiLure

No phase Interventional Belgium

Heart Failure · Non-ischemic Cardiomyopathy · Ischemic Cardiomyopathy

Not yet recruiting NCT07248657☆ Save

Comprehensive Therapeutic Program For People With Multiple Sclerosis

No phase Interventional Czechia

Multiple Sclerosis · Neurorehabilitation · Rehabilitation

Recruiting NCT07256015☆ Save

Deucravacitinib for Patients With Moderate/Severe Psoriasis: A Real-Life Experience in Italy

— Observational Italy

Psoriasis

Recruiting NCT05767047☆ Save

A Study of Apremilast in Children With Oral Ulcers Associated With Behçet's Disease or Juvenile Psoriatic Arthritis

Phase III Interventional Greece, Israel +2

Behçet's Disease · Juvenile Psoriatic Arthritis

Recruiting NCT07256704☆ Save

Hypnosis and Attention in Patients With a Neurological Disease (Stroke, Traumatic Brain Injury and Multiple Sclerosis)

No phase Interventional Switzerland

Stroke · Traumatic Brain Injury · Multiple Sclerosis