Гематология — клинические исследования

Acute Lymphoblastic Leukemia · Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent · Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory

Идёт набор NCT04162353

BCMA-CD19 cCAR in Multiple Myeloma and Plasmacytoid Lymphoma

Фаза I С лечением Китай

Multiple Myeloma in Relapse · Refractory Multiple Myeloma · Plasmacytoid; Lymphoma

Идёт набор NCT06948981

GT719 Injection for the Treatment of Recurrent/Refractory CD19 Positive Adult B-cell Malignancies

Фаза I / Фаза II С лечением Китай

Hematological Malignancy (Leukemia- Lymphoma)

Идёт набор NCT06007794

Correlation Between Ultrasound-assessed Quadriceps Muscle Mass and Baseline Whole-body Densitometry Muscle Index in the Post-cancer Population (JUMP Research II)

Без фазы С лечением Франция

Cancer · Post-cancer · Hematology

Идёт набор NCT05698147

Selinexor in Combination With MTX+Ritu to Treat R/R CNSL

Фаза I / Фаза II С лечением Китай

Central Nervous System Lymphoma

Идёт набор NCT06735664

Zanubrutinib in Combination With Odronextamab for the Treatment of Patients With Richter's Transformation

Фаза I С лечением США

Recurrent Transformed Chronic Lymphocytic Leukemia · Refractory Transformed Chronic Lymphocytic Leukemia · Richter Syndrome

Идёт набор NCT05658640

HEM iSMART-D: Trametinib + Dexamethasone + Chemotherapy in Children With Relapsed or Refractory Hematological Malignancies

Фаза I / Фаза II С лечением Австрия, Бельгия +13

Acute Lymphoblastic Leukemia, in Relapse · Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent · Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent

Идёт набор NCT05745714

HEM-iSMART-C: Ruxolitinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies

Фаза I / Фаза II С лечением Австрия, Бельгия +12

Acute Lymphoblastic Leukemia, in Relapse · Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent · Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent

Идёт набор NCT05751044

HEM-iSMART-B: Dasatinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies

Фаза I / Фаза II С лечением Австрия, Бельгия +12

Acute Lymphoblastic Leukemia · Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent · Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent

Идёт набор NCT06947967

Tucidinostat in Combination With CHOP in Newly Diagnosed Peripheral T-Cell Lymphoma With Follicular Helper of T Cell Phenotype

Фаза III С лечением Китай

Lymphoma, T-Cell, Peripheral

Идёт набор NCT06082102

Efficacy and Safety of Orelabrutinib Combined With Rituximab Versus Lenalidomide Combined With Rituximab in Patients With Relapsed/Refractory Marginal Zone Lymphoma

Фаза III С лечением Китай

Relapsed/Refractory Marginal Zone Lymphoma

Набор скоро начнётся NCT07045168

Risk-adapted Therapeutic Strategy in +1q NDMM

— Наблюдательное Китай

Multiple Myeloma

Идёт набор NCT06133426

Evaluation of the Role of Connected Scales in the Therapeutic Care of Hematology Patients

Без фазы С лечением Франция

Lymphoma, Non-Hodgkin · Myeloma Multiple

Идёт набор NCT06918834

Efficacy of Immediate Allogeneic Hematopoietic Stem Cell Transplantation Versus Bridging Therapy Followed by Transplantation in Higher-Risk Myelodysplastic Syndrome Patients

Фаза II С лечением Китай

Myelodysplastic Syndromes

Идёт набор NCT05305859

Venetoclax Combining Chidamide and Azacitidine (VCA) in the Treatment of R/R AML

Фаза II С лечением Китай

Leukemia, Myeloid, Acute · Relapsed Adult AML · Refractory Leukemia

Идёт набор NCT07168317

Tislelizumab , Cyclophosphamide, Mitoxantrone Liposomes, Chidamide, and Prednisone in the Treatment of New Diagnosed AITL

Фаза II С лечением Китай

New Diagnosed Angioimmunoblastic T-Cell Lymphoma

Идёт набор NCT05942885

Hypnosis: a Path to Appeasement

Без фазы С лечением Франция

Hematologic Cancer

Идёт набор NCT05357651

A Study to Assess the Safety and Efficacy of LB1410 in Participants With Advanced Solid Tumor or Lymphoma（Keyplus-001）

Фаза I С лечением Китай

Solid Tumor · Lymphoma

Набор скоро начнётся NCT07157514

Radioimmunotherapy Conditioning With 131I- Apamistamab for Allogeneic Transplant in Relapse/Refractory AML

Фаза II / Фаза III С лечением —

Acute Leukemia · Myeloid Leukemia · Acute Myelogenous Leukemia

Идёт набор NCT07165535

Quality of Life and Care Organization of Patients With Chronic Myeloid Leukemia in the Lombardy Hematology Network

— Наблюдательное Италия

Chronic Myeloid Leukemia (CML)

Идёт набор NCT06933277

Observational Study on the Combination of Selinexor With Bortezomib and Dexamethasone for the Treatment of MM Patients

— Наблюдательное Италия

Multiple Myeloma

Набор скоро начнётся NCT07162571

This is a Phase I/II Interventional, Open-label Treatment Study Designed to Evaluate the Safety and Efficacy of Anti CD 19/22 CAR- T Cells Immunotherapy for Adults With Relapsed or Refractory Acute Lymphoblastic Leukemia/Lymphoma.

Фаза I / Фаза II С лечением Беларусь

Acute Lymphobkastic Leukemia · B Cell Lymphoma

Набор скоро начнётся NCT07162532

Clinico-hematological and Molecular Characteristics of Chronic Lymphocytic Leukemia Patients

— Наблюдательное —

Chronic Lymphocytic Leukemia (CLL)

Идёт набор NCT05107674

A Study of NX-1607 in Adults With Advanced Malignancies

Фаза I С лечением США, Великобритания

Ovarian Cancer, Epithelial · Gastric Cancer · GastroEsophageal Junction (GEJ) Cancer

Идёт набор NCT07162116

A Study to Evaluate the Effect of XY0206 on the QTc Interval in Chinese Healthy Participants

Фаза I С лечением Китай

Acute Myeloid Leukemia With FLT3/ITD Mutation

Идёт набор NCT06383338

A Study Investigating the Change in Metabolism Phenotype in Paediatric, Adolescent & Young Adults With Hodgkin or Non-Hodgkin Lymphoma.

Фаза I С лечением Австралия

Hodgkin Lymphoma · Non Hodgkin Lymphoma

Идёт набор NCT05884333

Cord Blood Transplant in Adults With Blood Cancers

Фаза II С лечением США

Acute Myelogenous Leukemia (AML) · Acute Lymphoblastic Leukemia (ALL) · Chronic Myelogenous Leukemia (CML)

Идёт набор NCT04385290

Combination of Midostaurin and Gemtuzumab Ozogamicin in First-line Standard Therapy for Acute Myeloid Leukemia (MOSAIC)

Фаза I / Фаза II С лечением Германия

Acute Myeloid Leukemia

Идёт набор NCT07159620

Venetoclax Combined With Azacitidine, Chidamide, Vindesine, and Dexamethasone in Newly Diagnosed ETP-ALL Like Patients

Фаза II С лечением Китай

Adult T-cell Leukemia/Lymphoma

Набор скоро начнётся NCT07159906

Homoharringtonine, BCL-2 Inhibitor, Rituximab, and Prednisone in Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Фаза I / Фаза II С лечением Китай

Diffuse Large B-Cell Lymphoma · Relapsed Non-Hodgkin Lymphoma · Refractory Non-Hodgkin Lymphoma

Идёт набор NCT05728658

The Study of ICP-248 in Patients With Mature B-cell Malignancies

Фаза I С лечением Китай

Hematological Malignancies

Идёт набор NCT07115667

Radiation Combined With BCMA/CD3 Bispecific Antibody Therapy for Solitary Bone Plasmacytoma With Mild Bone Marrow Infiltration

Фаза II С лечением Китай

Solitary Bone Plasmacytoma · Plasmacytoma of Bone · Plasma Cell Disorders

Идёт набор NCT07160023

Local Registry of Primary Cutaneous T-cell Lymphomas

— Наблюдательное Италия

Primary Cutaneous T-cell Lymphomas NCT Number

Набор скоро начнётся NCT07157579

Notch 1 Mutation in Chronic Lymphocytic Leukemia and Non-Hodgkin's Lymphoma Patient

— Наблюдательное —

Chronic Lymphocytic Leukemia (CLL)- Non-Hodgins's Lymphoma (NHL)

Идёт набор NCT05372354

A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or Refractory Multiple Myeloma

Фаза I / Фаза II С лечением США, Канада +3

Multiple Myeloma

Идёт набор NCT06160843

Pembrolizumab and Olaparib Treatment for Relapsed or Refractory Peripheral T-Cell Lymphoma

Фаза II С лечением Сингапур

Relapsed Peripheral T-Cell Lymphoma · Refractory Peripheral T-Cell Lymphoma

Набор скоро начнётся NCT07158294

Identification of BCR::ABL1 Mutations by Digital PCR in CML

Без фазы С лечением —

Chronic Myeloid Leukemia (CML)

Идёт набор NCT06374602

Efficacy of Pembrolizumab and Lenvatinib in Patients With Anaplastic Thyroid Cancer

Фаза II С лечением Россия

Anaplastic Thyroid Cancer

Идёт набор NCT07154394

Cardiac Amyloid Deposits and Heart Dysfunction in Alzheimer's Disease

— Наблюдательное Германия

Dementia, Alzheimer Type · Mild Cognitive Impairment · Cardiac Amyloidosis

Набор скоро начнётся NCT07155395

Inflammatory and Hematological Indices in Diabetic STEMI Patients Undergoing Primary PCI

— Наблюдательное —

STEMI · Diabete Mellitus

Идёт набор NCT07154381

Hybrid Florbetaben PET/MRI for Imaging of Cardiac Amyloidosis

— Наблюдательное Германия

Cardiac Amyloidosis

Идёт набор NCT03081910

Autologous T-Cells Expressing a Second Generation CAR for Treatment of T-Cell Malignancies Expressing CD5 Antigen

Фаза I С лечением США

T-cell Acute Lymphoblastic Lymphoma · T-non-Hodgkin Lymphoma · T-cell Acute Lymphoblastic Leukemia

Идёт набор NCT07155954

Value of Super-resolution Ultrasonography in Differentiating Benign and Malignant Lymph Nodes

— Наблюдательное Китай

Lymphadenopathy · Lymphnode Metastasis · Lymphoma

Идёт набор NCT06429098

Study of A Venetoclax-based, Anthracycline-free Regimen in Newly Diagnosed CBFβ::MYH11(+) AML

Фаза II С лечением Китай

Acute Myeloid Leukemia

Идёт набор NCT03783416

SIZOMUS Safety of Ixazomib Targeting Plasma Cells in Multiple Sclerosis

Фаза I С лечением Великобритания

Relapsing Remitting Multiple Sclerosis · Primary Progressive Multiple Sclerosis · Secondary Progressive Multiple Sclerosis

Идёт набор NCT07152041

Newly-diagnosed Pediatric Ph-positive B-ALL Protocol

Фаза III С лечением Китай, Гонконг

Acute Lymphoblastic Leukemia (ALL) Philadelphia Chromosome-positive (Ph+) · Childhood Leukemia, Acute Lymphoblastic

Идёт набор NCT06382168

DFP-10917 in Combination With Venetoclax in Relapsed or Refractory Acute Myeloid Leukemia

Фаза I / Фаза II С лечением США

Leukemia, Myeloid, Acute

Набор скоро начнётся NCT07025824

Evaluation of Treosulfan Versus Melphalan Conditioning Followed by PTCy in Patients With AML and MDS Undergoing Allogeneic Transplantation

Фаза II С лечением Германия

AML - Acute Myeloid Leukemia · MDS (Myelodysplastic Syndrome)

Набор скоро начнётся NCT07150676

Harmonized Clinical and Biological Database for Integrated Research Into the Management of Pediatric Acute Myeloid Leukemia

— Наблюдательное —

Acute Myeloid Leukemia (AML) · Pediatric Acute Myeloid Leukemia

Идёт набор NCT06354322

Unclassified GENotypes of Autoinflammatory Diseases and AA Amyloidosis

— Наблюдательное Франция

AA Amyloidosis · Autoinflammatory Disease

Идёт набор NCT03911128

A Treatment Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia

— Наблюдательное Дания, Эстония +6

Leukemia, Acute Lymphoblastic

Идёт набор NCT05208307

Belantamab Mafodotin, Pomalidomide and Dexamethasone for the Treatment of High-Risk Myeloma

Фаза II С лечением США

Plasma Cell Myeloma

Идёт набор NCT07014865

Factors Associated With Health-related Quality of Life and Social Participation of Patients With Multiple Myeloma and Their Caregivers

— Наблюдательное Италия

Multiple Myeloma (MM) · Hematologic Neoplasm

Набор скоро начнётся NCT07146542

Expression Pattern and Possible Clinical Significance of CD81 In Myeloid Leukemia

— Наблюдательное —

Acute Myeloid Leukemia · Chronic Myeloid Leukemia

Набор скоро начнётся NCT07145359

Virtual Reality Intervention for Symptom Management in Stem Cell Transplantation

Без фазы С лечением —

Cancer and / or Hematological Malignancy · Hematopoetic Stem Cell Transplantation · Nursing Interventions

Идёт набор NCT06523699

Impact of Recombinant Human Interleukin-7 (CYT107) on Tumor Clearance and Immune Reconstitution in Multiple Myeloma Patients After Autologous Hematopoietic Cell Transplant

Фаза I С лечением США

Multiple Myeloma

Набор скоро начнётся NCT07143877

Prognostic Impacts of Lipid Profile and BMI in Adult AML

— Наблюдательное Египет

AML (Acute Myeloid Leukemia) · BMI · Lipid Profile

Набор скоро начнётся NCT07144657

Prospective Study of Frontline Antibiotics Therapy in the Treatment of Early-stage HP-negative Gastric MALT Lymphoma

Фаза II С лечением Тайвань

MALT Lymphoma of Stomach

Набор скоро начнётся NCT07143864

Efficacy and Safety of Stapokibart for Primary Cutaneous Amyloidosis

Без фазы С лечением —

Primary Cutaneous Amyloidosis

Идёт набор NCT06855810

Newly-diagnosed Pediatric T-cell ALL Protocol

Фаза II / Фаза III С лечением Китай, Гонконг

Acute Lymphoblastic Leukemia · Childhood Leukemia, Acute Lymphoblastic · T Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma

Идёт набор NCT06908629

Addressing Social Determinants of Health Among Metro Detroit Cancer Survivors

Без фазы С лечением США

Cancer · Cancer Survivors · Gastrointestinal Cancers

Идёт набор NCT03850574

Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia

Фаза I / Фаза II С лечением США, Австралия +4

Leukemia, Myeloid, Acute · Refractory AML · Relapsed Adult AML

Идёт набор NCT06882057

Newly-diagnosed Low Risk Pediatric B-cell ALL Protocol

Фаза II / Фаза III С лечением Китай, Гонконг

Acute Lymphoblastic Leukemia ALL · Childhood Leukemia, Acute Lymphoblastic · B Cell Acute Lymphoblastic Leukemia (B-ALL)

Набор скоро начнётся NCT07139353

Linperlisib Combined With Chidamide in the Treatment of Relapsed or Refractory Peripheral T-cell Lymphoma

Фаза I / Фаза II С лечением —

Peripheral T Cells Lymphoma (PTCL)

Идёт набор NCT07016165

Ciprofloxacin vs Ceftazidime for Empirical Treatment of High-Risk Neutropenic Fever in Children With Hematologic Malignancies

Фаза IV С лечением Индонезия

Neutropenic Fever · Acute Lymphoblastic Leukemia · Acute Myeloblastic Leukemia

Набор скоро начнётся NCT07035379

A Phase I/II Study of TRS005 in Combination With Cyclophosphamide, Doxorubicin, and Prednisone（T-CHP） in Previously Untreated Patients With CD20-positive DLBCL

Фаза I / Фаза II С лечением Китай

Diffuse Large B-Cell Lymphoma (DLBCL)

Набор скоро начнётся NCT07138261

Taiwanese Anaplastic Thyroid Cancer Registry

— Наблюдательное Тайвань

Thyroid Carcinoma, Anaplastic

Набор скоро начнётся NCT06886139

A Phase 2 Study of TRS005 in Patients With CD20-positive R/R DLBCL.

Фаза II С лечением Китай

CD20-positive Diffuse Large B-Cell Lymphoma

Идёт набор NCT07135778

Liposomal Amphotericin B and Isavuconazole/Posaconazole in Br-IFD（ Breakthrough Invasive Fungal Disease） in Patients With Malignant Hematological Diseases

— Наблюдательное Китай

Invasive Fungal Disease

Идёт набор NCT05691608

MoleculAr Profiling for Pediatric and Young Adult Cancer Treatment Stratification 2

Без фазы С лечением Франция

Solid Tumor · Leukemia

Идёт набор NCT05039073

Brentuximab Vedotin and Nivolumab for the Treatment of Relapsed/Refractory Classic Hodgkin Lymphoma Previously Treated With Brentuximab Vedotin or Checkpoint Inhibitors

Фаза II С лечением США

Recurrent Classic Hodgkin Lymphoma · Refractory Classic Hodgkin Lymphoma

Идёт набор NCT07081022

JS203 Combination Regimens in B-Cell Non-Hodgkin's Lymphoma

Фаза II С лечением Китай

B-cell Non-Hodgkin's Lymphoma

Идёт набор NCT06159491

Pacritinib in CMML

Фаза I / Фаза II С лечением США

Chronic Myelomonocytic Leukemia

Идёт набор NCT06887283

Essen Amyloidosis Registry

— Наблюдательное Германия

Amyloidosis; Systemic · Amyloidosis Cardiac

Набор скоро начнётся NCT07131449

Serum Histone Succinylation as a Novel Prognostic Biomarker in Hematological Malignancies

— Наблюдательное —

Leukemia · Lymphoma